ID I2DVY1_9BURK Unreviewed; 771 AA.
AC I2DVY1;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Tyrosine-protein kinase Wzc {ECO:0000313|EMBL:AFJ88807.1};
GN ORFNames=MYA_4453 {ECO:0000313|EMBL:AFJ88807.1};
OS Burkholderia sp. KJ006.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=416344 {ECO:0000313|EMBL:AFJ88807.1, ECO:0000313|Proteomes:UP000010108};
RN [1] {ECO:0000313|EMBL:AFJ88807.1, ECO:0000313|Proteomes:UP000010108}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KJ006 {ECO:0000313|EMBL:AFJ88807.1,
RC ECO:0000313|Proteomes:UP000010108};
RX PubMed=22843575; DOI=10.1128/JB.00821-12;
RA Kwak M.J., Song J.Y., Kim S.Y., Jeong H., Kang S.G., Kim B.K., Kwon S.K.,
RA Lee C.H., Yu D.S., Park S.H., Kim J.F.;
RT "Complete Genome Sequence of the Endophytic Bacterium Burkholderia sp.
RT Strain KJ006.";
RL J. Bacteriol. 194:4432-4433(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003515; AFJ88807.1; -; Genomic_DNA.
DR RefSeq; WP_014725013.1; NC_017921.1.
DR AlphaFoldDB; I2DVY1; -.
DR KEGG; buk:MYA_4453; -.
DR PATRIC; fig|416344.3.peg.4528; -.
DR HOGENOM; CLU_009912_0_0_4; -.
DR Proteomes; UP000010108; Chromosome 2.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05387; BY-kinase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR025669; AAA_dom.
DR InterPro; IPR032807; GNVR.
DR InterPro; IPR003856; LPS_length_determ_N_term.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR32309; TYROSINE-PROTEIN KINASE; 1.
DR PANTHER; PTHR32309:SF13; TYROSINE-PROTEIN KINASE ETK-RELATED; 1.
DR Pfam; PF13614; AAA_31; 1.
DR Pfam; PF13807; GNVR; 1.
DR Pfam; PF02706; Wzz; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000313|EMBL:AFJ88807.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:AFJ88807.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..114
FT /note="Polysaccharide chain length determinant N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02706"
FT DOMAIN 396..470
FT /note="Tyrosine kinase G-rich"
FT /evidence="ECO:0000259|Pfam:PF13807"
FT DOMAIN 550..687
FT /note="AAA"
FT /evidence="ECO:0000259|Pfam:PF13614"
SQ SEQUENCE 771 AA; 83702 MW; 10EED48821162D60 CRC64;
MTLDRAASNE YRDGAGSISR DAPRFALTEL LENVLDYRYA FISVFLGCFL LALIYAVSAA
PVYSVDTLIQ VQENKHSALG ALSEISNALD IQNSAVIGEI DVARSRTVVT QAIEETVAQA
EATVGNRIPL VGGFVESVLP KDADGLVIAP FSTPFFAWGG ERIEFRRFDV PESQIDKKLE
LDYLAGNRFS LKDSDGQEVL KGVIGKPSEA NGYRVDIARI VARAGTEFRV RRVTTAERLD
SVLTKLAGAE TKRQSGIMQL SLESRDPVSA ARLLNAIAAA YLDVNARRRS EDAEHSLAFL
ETQLPVVKAR LEQAEQALNS FRNAQGSIDS QGDVRLLIDQ LALVDKARLE AKLEYQDLSS
KYVAGQPQLT AVVNKLKTLD QQSAELKDKV AHLPSQQQTY LRLARDVEVN NQLYVGLLNN
TQQLQIAKAG TVGNASIVDK AVPTDKPIRP KRMLVLALGA AVGLILGAAA AQGYAWFFRR
VRDPKHLEAA VGVPMLGILP SLPQPVDGDA LGRPASVAVR DDPDTPLAEA LANLALLLRC
KTGVEHGRSK TVLITSPEPG QGKSMIAANL ACLFAEDGLK TLLLRADARQ SGIEHALRVK
ADRGLSDVLK QSLDPERAIR RVDENLDVLP AGTHAQPARN LYGADKLDAL LARLRSQYDM
IVVDAPLTRP AANVAMLARF ADITLMVARQ GSIGSADVAE AVENLQRIGA KVDGLVFNGF
DPSPLRYGYY ANAYRDAKGP RAQPDRRDVA AETFLFRAWT RVRKELLGKA A
//
