ID I2F746_9BACT Unreviewed; 336 AA.
AC I2F746;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Mannose-1-phosphate guanylyltransferase {ECO:0000313|EMBL:AFK07749.1};
GN ORFNames=Theba_2115 {ECO:0000313|EMBL:AFK07749.1};
OS Mesotoga prima MesG1.Ag.4.2.
OC Bacteria; Thermotogota; Thermotogae; Kosmotogales; Kosmotogaceae; Mesotoga.
OX NCBI_TaxID=660470 {ECO:0000313|EMBL:AFK07749.1, ECO:0000313|Proteomes:UP000002881};
RN [1] {ECO:0000313|EMBL:AFK07749.1, ECO:0000313|Proteomes:UP000002881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mesG1.Ag.4.2 {ECO:0000313|Proteomes:UP000002881};
RX PubMed=22798451;
RA Zhaxybayeva O., Swithers K.S., Foght J., Green A.G., Bruce D., Detter C.,
RA Han S., Teshima H., Han J., Woyke T., Pitluck S., Nolan M., Ivanova N.,
RA Pati A., Land M.L., Dlutek M., Doolittle W.F., Noll K.M., Nesbo C.L.;
RT "Genome Sequence of the Mesophilic Thermotogales Bacterium Mesotoga prima
RT MesG1.Ag.4.2 Reveals the Largest Thermotogales Genome To Date.";
RL Genome Biol. Evol. 4:700-708(2012).
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DR EMBL; CP003532; AFK07749.1; -; Genomic_DNA.
DR RefSeq; WP_014731522.1; NC_017934.1.
DR AlphaFoldDB; I2F746; -.
DR STRING; 660470.Theba_2115; -.
DR KEGG; mpg:Theba_2115; -.
DR eggNOG; COG0836; Bacteria.
DR HOGENOM; CLU_035527_0_1_0; -.
DR Proteomes; UP000002881; Chromosome.
DR GO; GO:0004475; F:mannose-1-phosphate guanylyltransferase (GTP) activity; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd02509; GDP-M1P_Guanylyltransferase; 1.
DR InterPro; IPR049577; GMPP_N.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR46390; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR PANTHER; PTHR46390:SF1; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF159283; Guanosine diphospho-D-mannose pyrophosphorylase/mannose-6-phosphate isomerase linker domain; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000313|EMBL:AFK07749.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002881};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AFK07749.1}.
FT DOMAIN 6..273
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 336 AA; 38382 MW; 232DE9D8067D5478 CRC64;
MYVVRTLIMA GGIGERLWPV SVKKRPKQFH KFGSSKTMIE ETIERMEKVT DEIIIITTRE
QFPLMQYYLP LFPGENVIFE PMRRNTAPAI ALGSTRFSPD DIMVVVPADH VIRDEESFLK
TLNKAIKYAE SNDSLVTIGI TPTYPYTGYG YIERGNAVDD NEEVYSVKKF HEKPDYETAQ
HYVQSGRFLW NSGIFVWKKS VFDLELSKNF PDLFSAISEI SKRPEDIEKI YERLPKISID
YGLMERSSKV ATVPASFYWN DIGSWDAVYD LLIKDKNGNA VEGEFSLKDV KNCLLINHTQ
KKLAVSGIEG FILVATSEGT LVCRRGESQD IKEIIK
//
