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Database: UniProt
Entry: I2FW40_USTH4
LinkDB: I2FW40_USTH4
Original site: I2FW40_USTH4 
ID   I2FW40_USTH4            Unreviewed;       855 AA.
AC   I2FW40;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   07-SEP-2016, entry version 15.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=UHOR_01002 {ECO:0000313|EMBL:CCF51133.1};
OS   Ustilago hordei (strain Uh4875-4) (Barley covered smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=1128400 {ECO:0000313|Proteomes:UP000006174};
RN   [1] {ECO:0000313|EMBL:CCF51133.1, ECO:0000313|Proteomes:UP000006174}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Uh4875-4 {ECO:0000313|Proteomes:UP000006174};
RX   PubMed=22623492; DOI=10.1105/tpc.112.097261;
RA   Laurie J.D., Ali S., Linning R., Mannhaupt G., Wong P., Gueldener U.,
RA   Muensterkoetter M., Moore R., Kahmann R., Bakkeren G., Schirawski J.;
RT   "Genome comparison of barley and maize smut fungi reveals targeted
RT   loss of RNA silencing components and species-specific presence of
RT   transposable elements.";
RL   Plant Cell 24:1733-1745(2012).
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CCF51133.1}.
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DR   EMBL; CAGI01000161; CCF51133.1; -; Genomic_DNA.
DR   EnsemblFungi; CCF51133; CCF51133; UHOR_01002.
DR   OrthoDB; EOG092C0YCY; -.
DR   Proteomes; UP000006174; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006174};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006174};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    420    448       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    469    489       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    547    568       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    580    600       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    648    672       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    791    818       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED      105    146       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   855 AA;  96843 MW;  BC6002F750BE6AA1 CRC64;
     MPEEESLFRS ATMSLIQLYI PSETAHATVQ ELGELGNVMF KDLNPDVSPF QRSFVTDIRR
     LDEMERRIRF LYTQMEKEGV PVRPLESALP FISLGSDGRR GPQLMDELSV KLREHEERLG
     QMNGSYETLQ KRLQELEEAK HVLRETAVFF DQAEGRQDAV RASVDDANAP LLHDVESHVF
     NTSHGDDNNY GTFDLEFVAG TIDRSKMAIF ERILWRVLRG NLYMNYAEIE EAFDDPTKEE
     PVRKNVFIIF AHGAELLAKI RKISESMGGT LYPIDSNADR REESLREVLS RIEDLNNVLY
     STSATRRTEL VKIAEVLSAW EDVVRKEKLI YSTLNMFLFD NRRKTLVAEG WCPSSDLGQI
     QLALRRATEN AGTSAPAVLQ ELRTNKSPPT FQRSNKYTEA IQSVGDSYGI AKYKEVNPGL
     FNFILLPFLF AVMFGDVFHA FLMTLAALAM CTFERKLAKV DNEIFTMFFY GRYMMLLMGV
     FSMFTGFLYN DIGSKSMHLF HTGWDWPHNE GTIEAVPNGN VYAIGIDPSW HGADNALVFT
     NSLKMKMSVI LGVFHMTLAI LLNVPNFIRF GQKWKIWSEI VPQMLFMQSL FGYLVFAIVY
     KWSIDWYETD ANGTVFRNNP PGLLNMLIYM FLKPGTVDPK TELFRGQAFV QTMLLLIAFV
     CVPWMLVVTP YIEWKEHQKI KGQGYRAVGV NNGSRGFGLD DDADDDADAD ESSRLTQGQG
     NGHGSGGHGD GEMEEEHKFN IGEAVIHQVI HTIEFCLGCI SNTASYLRLW ALSLAHAQLS
     EVLWTMTIQN VFGMTGVTGA IATVLAFGLW FCLSIAILCC MEGLSSLLHA IRLAWVEFGS
     KFYQAGGYQF EPLKF
//
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