ID   I2GC06_9BACT            Unreviewed;       438 AA.
AC   I2GC06;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Peptidase U62 modulator of DNA gyrase {ECO:0000313|EMBL:CCH51430.1};
GN   Name=tldD3 {ECO:0000313|EMBL:CCH51430.1};
GN   ORFNames=BN8_00353 {ECO:0000313|EMBL:CCH51430.1};
OS   Fibrisoma limi BUZ 3.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC   Fibrisoma.
OX   NCBI_TaxID=1185876 {ECO:0000313|EMBL:CCH51430.1, ECO:0000313|Proteomes:UP000009309};
RN   [1] {ECO:0000313|EMBL:CCH51430.1, ECO:0000313|Proteomes:UP000009309}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BUZ 3T {ECO:0000313|Proteomes:UP000009309};
RX   PubMed=22843583; DOI=10.1128/jb.00869-12;
RA   Filippini M., Qi W., Jaenicke S., Goesmann A., Smits T.H., Bagheri H.C.;
RT   "Genome Sequence of the Filamentous Bacterium Fibrisoma limi BUZ 3T.";
RL   J. Bacteriol. 194:4445-4445(2012).
CC   -!- SIMILARITY: Belongs to the peptidase U62 family.
CC       {ECO:0000256|ARBA:ARBA00005836}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCH51430.1}.
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DR   EMBL; CAIT01000004; CCH51430.1; -; Genomic_DNA.
DR   RefSeq; WP_009280018.1; NZ_CAIT01000004.1.
DR   AlphaFoldDB; I2GC06; -.
DR   STRING; 1185876.BN8_00353; -.
DR   eggNOG; COG0312; Bacteria.
DR   OrthoDB; 9763230at2; -.
DR   Proteomes; UP000009309; Unassembled WGS sequence.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR   InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR   InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR   InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR   InterPro; IPR035068; TldD/PmbA_N.
DR   InterPro; IPR036059; TldD/PmbA_sf.
DR   PANTHER; PTHR43666:SF1; CONSERVED PROTEIN; 1.
DR   PANTHER; PTHR43666; TLDD PROTEIN; 1.
DR   Pfam; PF01523; PmbA_TldD_1st; 1.
DR   Pfam; PF19290; PmbA_TldD_2nd; 1.
DR   Pfam; PF19289; PmbA_TldD_3rd; 1.
DR   SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009309}.
FT   DOMAIN          31..89
FT                   /note="Metalloprotease TldD/E N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01523"
FT   DOMAIN          146..214
FT                   /note="Metalloprotease TldD/E central"
FT                   /evidence="ECO:0000259|Pfam:PF19290"
FT   DOMAIN          222..432
FT                   /note="Metalloprotease TldD/E C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19289"
SQ   SEQUENCE   438 AA;  47535 MW;  5003FD795380553B CRC64;
     MAILSKEEAK KIIDKVLSFS KADEMSVNLG GGRTGNIRYA RNSVSTSGES NNLSLGITAV
     FGKRSGTATI NEFDDASLEK TVRRAEEIAR LAPENPEYVP ALGPQQYVDT KAYVESTAKI
     DPAYRAQAAF DSIDLCNKKN LTAAGYLEDS AGFSAIGNSK GLFGYNPATS VDFSITVRTA
     DGTGSGYAIR DVNDVSKLST KSATDVAVQK ALASTSAKAL EPGKYTVILE PAASVDLLQN
     MMRSIDARNA DEGRSFLSKK GGGTRLGEKL YDERVTIYSD PTNADIPGSP YSGDGRPQEK
     IVWVDKGVVK NMTYSRFWAE KKGVKAVPSP SGFIMEGGTQ SLADLIKSTE KGILVTRFWY
     IRFVDPQTLL YTGLTRDGTF YIENGQIKFP VKNFRFNESP VIMLNNLEAM GRPVRVSGNM
     VPPLKIRDFT FTSLSDAV
//