ID I2GH13_9BACT Unreviewed; 721 AA.
AC I2GH13;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:CCH53188.1};
DE EC=2.7.3.- {ECO:0000313|EMBL:CCH53188.1};
GN ORFNames=BN8_02264 {ECO:0000313|EMBL:CCH53188.1};
OS Fibrisoma limi BUZ 3.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC Fibrisoma.
OX NCBI_TaxID=1185876 {ECO:0000313|EMBL:CCH53188.1, ECO:0000313|Proteomes:UP000009309};
RN [1] {ECO:0000313|EMBL:CCH53188.1, ECO:0000313|Proteomes:UP000009309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BUZ 3T {ECO:0000313|Proteomes:UP000009309};
RX PubMed=22843583; DOI=10.1128/jb.00869-12;
RA Filippini M., Qi W., Jaenicke S., Goesmann A., Smits T.H., Bagheri H.C.;
RT "Genome Sequence of the Filamentous Bacterium Fibrisoma limi BUZ 3T.";
RL J. Bacteriol. 194:4445-4445(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCH53188.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAIT01000006; CCH53188.1; -; Genomic_DNA.
DR AlphaFoldDB; I2GH13; -.
DR STRING; 1185876.BN8_02264; -.
DR eggNOG; COG0457; Bacteria.
DR eggNOG; COG4585; Bacteria.
DR Proteomes; UP000009309; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF17874; TPR_MalT; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CCH53188.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009309};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CCH53188.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 460..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 221..254
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 302..335
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 523..712
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 418..454
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 721 AA; 81796 MW; 362E699A89FE9F50 CRC64;
MGSHDVHRLE LHPHPAGSVF QERNAAGRQT LNSHYVRAGL LPETPSEKSD IATASVSLSG
NGTVKTFLML AQRLLILGSF LLLVHLRSVG QSVMTPSDTS YIMTLLRKAE AIEMQQPEKA
LLDYQKAYTF ARRIGYTKGY FESIRLTTYL LDLLGRHTES HKLATEGLQK ALRDTSEQYR
STCYFSLAQS AMFQGKNKEA IYYFKKAAPF MLAHRNRKKA AVLYQNLGLM YEAEKLYPQA
LDYFNRALKY DLIAKSPQHE IALDYHSMAT VYVKQNQLPM ALAYFRRTKS LLRPDNDIHF
LTSLYGNIGN LHKELSHFDS SLYYYRSALR MNRELNNPLQ ELHLLAGLAE TYNEMKQFGQ
AKALLDNAYA LARQHKVGLS EFRNIYREYA NASLGLKDYK GAIPWYDKYI ETKDSLSTLE
AKTLLEEYEL KLRQAESRQK LTEKQRQIDQ LAQAHQRQQL WLLIAGLVAL VAVGSLVFAY
QYSRQRQRAS DNALLAAQRA HSLAVMQSEL QGQQKERLRI SKEMHDDLGA SLTAIGLLSE
VVKTRMGTQT APEVEKISTI SADMVTTMNE IIWSLNTRND SLNGLIAYTR AYTSEFIDNT
PLHLRTQVHE SPQEVTIQGT DRRNIFLTVK EALHNVVKHA QATEVSLTIR PETDRLLIEV
SDNGRGFEPN ERTRLRNGLT NMQNRMSNSG GSCTISSSPR GTTVAIIYPY PLSATANILQ
M
//
