ID   I2GVQ1_TETBL            Unreviewed;      1322 AA.
AC   I2GVQ1;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   24-JAN-2024, entry version 48.
DE   RecName: Full=Nuclear mRNA export factor {ECO:0000256|PIRNR:PIRNR037320};
GN   Name=TBLA0A04070 {ECO:0000313|EMBL:CCH58203.1};
GN   ORFNames=TBLA_0A04070 {ECO:0000313|EMBL:CCH58203.1};
OS   Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC
OS   10599 / NRRL Y-10934 / UCD 77-7) (Yeast) (Kluyveromyces blattae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX   NCBI_TaxID=1071380 {ECO:0000313|EMBL:CCH58203.1, ECO:0000313|Proteomes:UP000002866};
RN   [1] {ECO:0000313|EMBL:CCH58203.1, ECO:0000313|Proteomes:UP000002866}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 /
RC   UCD 77-7 {ECO:0000313|Proteomes:UP000002866};
RX   PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA   Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA   Wolfe K.H.;
RT   "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT   accidents.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC   -!- SUBCELLULAR LOCATION: Nucleus envelope {ECO:0000256|PIRNR:PIRNR037320}.
CC   -!- SIMILARITY: Belongs to the SAC3 family. {ECO:0000256|ARBA:ARBA00038443,
CC       ECO:0000256|PIRNR:PIRNR037320}.
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DR   EMBL; HE806316; CCH58203.1; -; Genomic_DNA.
DR   RefSeq; XP_004177722.1; XM_004177674.1.
DR   STRING; 1071380.I2GVQ1; -.
DR   GeneID; 14493095; -.
DR   KEGG; tbl:TBLA_0A04070; -.
DR   eggNOG; KOG1860; Eukaryota.
DR   HOGENOM; CLU_006094_0_0_1; -.
DR   InParanoid; I2GVQ1; -.
DR   OMA; FQGTCLD; -.
DR   OrthoDB; 91913at2759; -.
DR   Proteomes; UP000002866; Chromosome 1.
DR   GO; GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.
DR   GO; GO:0070390; C:transcription export complex 2; IEA:UniProtKB-UniRule.
DR   GO; GO:0006406; P:mRNA export from nucleus; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:UniProt.
DR   GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.5.1760; -; 1.
DR   Gene3D; 1.25.40.990; -; 1.
DR   InterPro; IPR000717; PCI_dom.
DR   InterPro; IPR017173; Sac3.
DR   InterPro; IPR045107; SAC3/GANP/THP3.
DR   InterPro; IPR005062; SAC3/GANP/THP3_conserved.
DR   InterPro; IPR024293; SAC3_helical.
DR   PANTHER; PTHR12436; 80 KDA MCM3-ASSOCIATED PROTEIN; 1.
DR   PANTHER; PTHR12436:SF3; GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN; 1.
DR   Pfam; PF12209; SAC3; 1.
DR   Pfam; PF03399; SAC3_GANP; 1.
DR   PIRSF; PIRSF037320; mRNA_export_factor_Sac3; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|PIRNR:PIRNR037320};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002866}.
FT   DOMAIN          317..506
FT                   /note="PCI"
FT                   /evidence="ECO:0000259|PROSITE:PS50250"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          708..779
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..34
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        708..739
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        748..774
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1322 AA;  151397 MW;  54A02B2AEC1BE4DD CRC64;
     MNPLLSGKSK PSNNNNNYNN NNNGNIFLNK KDNNNNSKFK QKFNHKKFSN KKFNTDKINK
     NEIPSNINSI KKDEIDSIIG PLLNNPQSMG FSQFKHEKRV LPRFLIGQRP QLVQRPLVQD
     PWDKANQLKM NQLESSINDL NELYETLKKM RNFERRIMES KGLVDKPALA KDLNDAIIFQ
     GTCMDMCPTF ERSRRNVEHT VLVYERDSSS DKKASRSKAL KVFARPAAAA EPPLPSDVRP
     PHILVKSLDY IIDNLLSTLP DSESFLWDRM RSIRQDFTYQ NYSGPEAVDC NERIVRIHLL
     ILHIMVKSNV EFSLQQELEQ LHKSLITLSE IYDDVRSTGG VCPNEAEFRA YALLSKIRDP
     EYDKTIQELP SSIFQDNLVQ FALCFRRIIS NSSFSERGYM KTESCLNFYS RFFQLLNSGN
     VPILLSFFLE IYLNEIRFYS LKALSLTLNK KYKPVSISIF KEYLSFNDFQ EIEAFCKYYS
     IDIQNDFIDL KSLTHHSHKL AEKKPLKQTI LLSIDSQLLS LSYIDLINSG LPNFTSTPIN
     DTKNVDNIID SIPLPIESNI FLPPIDLHPE EVTPKLEPPI IKPPIVNIST PNDNIDNKPT
     ISTNNKVTVT NNQQETIPQT ISFSRPEAPS FFQTSNSFNI GKQDTSLKQT FKTPNLETNF
     NKISTPNMTN FFQNQPKIDV FKTPVTKASE ESNNGLLSNI NNILNDKVPK TTLESSPSSR
     IQSKPKALPA SSFTPLASLD TKPKSLEKSE SQPSAGSFSP APRSSSTSNN DIKIDTARNE
     SDIEVTQSIN RKMQVIEELS TELFDAFFRE KIYLLSLETK ADMKYSSILK TRFINRWRSK
     YDNVINHKKR ETMQILEFQN VINELGKPNF KEPSEYLFTP NFKKTKHTNL LNSINKSLQL
     SPISNEVNIF STKIQKDSKI WEPFNLDNYY ETIASRCPNF EEAICDIFIY SKNYNPIIFQ
     WLLRKFNIND YRIPEKKILK NVSISINGID DKYDTSLFNN VQLLVFNTGV TNDDIFDLDL
     KLKQDGEDMI KLMTDIAVNT NIKFDILVVY WDSNDIQLSD KRLSKLLQLG KVSKNFRVCL
     NNIIIVRIGE TDPHNILLHG LNQISTSFKY SLTDKGRINL SLKNRRSLAG IGPQEVQLRA
     TDKLDAKLKK IQDNENAKLL GAIDKRNTYQ YLFSHVEASP RKTKRKLPVL LSESKSNKFR
     TPSGRNNTSS LSSFGNLSHL AKKGKNNMHN SNNILIFETP TYATINNRSY MTPGNVTKDS
     NDISYIRAQY IQHIPESNNS LLYNTPTNPP VSQFHAPMIS SPDNIANNLS ELRSLIDTVK
     KR
//