ID I2GWC4_TETBL Unreviewed; 855 AA.
AC I2GWC4;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Bromodomain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=TBLA0A06350 {ECO:0000313|EMBL:CCH58426.1};
GN ORFNames=TBLA_0A06350 {ECO:0000313|EMBL:CCH58426.1};
OS Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC
OS 10599 / NRRL Y-10934 / UCD 77-7) (Yeast) (Kluyveromyces blattae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX NCBI_TaxID=1071380 {ECO:0000313|EMBL:CCH58426.1, ECO:0000313|Proteomes:UP000002866};
RN [1] {ECO:0000313|EMBL:CCH58426.1, ECO:0000313|Proteomes:UP000002866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 /
RC UCD 77-7 {ECO:0000313|Proteomes:UP000002866};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HE806316; CCH58426.1; -; Genomic_DNA.
DR RefSeq; XP_004177945.1; XM_004177897.1.
DR AlphaFoldDB; I2GWC4; -.
DR STRING; 1071380.I2GWC4; -.
DR GeneID; 14493077; -.
DR KEGG; tbl:TBLA_0A06350; -.
DR eggNOG; KOG1474; Eukaryota.
DR HOGENOM; CLU_001499_4_0_1; -.
DR InParanoid; I2GWC4; -.
DR OMA; STSHHEY; -.
DR OrthoDB; 152619at2759; -.
DR Proteomes; UP000002866; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd05500; Bromo_BDF1_2_I; 1.
DR Gene3D; 1.20.1270.220; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR027353; NET_dom.
DR InterPro; IPR038336; NET_sf.
DR PANTHER; PTHR22880:SF225; BROMODOMAIN-CONTAINING PROTEIN BET-1; 1.
DR PANTHER; PTHR22880; FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; 1.
DR Pfam; PF17035; BET; 1.
DR Pfam; PF00439; Bromodomain; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 2.
DR SUPFAM; SSF47370; Bromodomain; 2.
DR PROSITE; PS00633; BROMODOMAIN_1; 2.
DR PROSITE; PS50014; BROMODOMAIN_2; 2.
DR PROSITE; PS51525; NET; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Reference proteome {ECO:0000313|Proteomes:UP000002866};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 200..272
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 383..455
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 621..701
FT /note="NET"
FT /evidence="ECO:0000259|PROSITE:PS51525"
FT REGION 1..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 287..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 561..623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 705..783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 795..855
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..179
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 340..355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..606
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 705..764
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 796..846
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 855 AA; 97888 MW; 0E452A526721BEF8 CRC64;
MSDSETRPVI DPGVGNSQTD EIQGSETRKR EMEVDEVDKS EDKDCHIEKK LKPDNGETEI
GQDKTELEED KKEPEQDGKE KEQDDKEQEK EAIVEETSKQ DSIPKVEEKE EPINDKESKE
ESKDETTKEE VKKENMKDET KQEETKDEKK PEEAKEEEPK DGMKIPAPAP PPEPDMNNLP
ENPIPAHQKK HALMAVKAVK RLKDSRPFLN PVDPVALNVP FYYNKIKHPM DLNTIERKLT
LNAYDVIESL TEDFNLMVNN CILFNGPTSS ISQMAKNIQA SFEKHMLNMP PRDLPTPVKN
SNSSNNPKQK VLNSEGSVII RRLQSNNGRP KREIHPPKSK DIYNTTSSAD NDSNSNRKPP
KSKKLKQVMK FCQSIVKELS SKKYSSFNYP FLVPVDPVEQ NIPTYFDYIK EPMDLSTISK
KLINWEYKTP EEVEYDINLI FKNCYIFNPE GTIVNMMGHR LQDIFNTKWA ERPIFDSYED
SEDEQLKQED QEEDGYEDES MFMSMDHDQM NGMEDLSDSD ADLDETSITN PAIQYLEEQL
KRMKSELQVL KRQELDKIRK ERRLAKYNSM QSNSNKKKKK NISNNGTANL NFSNNKKVST
PSGTNKKSIR SRRKNSKSNI SQPANKFKTV VTYDMKRIIT ERINDLPPEK LEKAIEIIKK
SMPYLSDDDE VELDLDTLDT NTILNLFNTF FRHFENIPSP NSISSNSHLH NNNQSNYNDD
YNNSNTFNTN INTPPTMDFM DSISMRSPLS PTSLANNLNN SSTHSHTNKK KRSKPLTQEQ
QSKQIEKIKN KLAFLDGASP NSNNGSSPSS STNLKNLSSS NNINSLKNNK RSNQTAYSTT
SSSSDDDVSS ESEEE
//
