ID   I2GX36_TETBL            Unreviewed;       730 AA.
AC   I2GX36;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
GN   Name=TBLA0A08990 {ECO:0000313|EMBL:CCH58688.1};
GN   ORFNames=TBLA_0A08990 {ECO:0000313|EMBL:CCH58688.1};
OS   Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC
OS   10599 / NRRL Y-10934 / UCD 77-7) (Yeast) (Kluyveromyces blattae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX   NCBI_TaxID=1071380 {ECO:0000313|EMBL:CCH58688.1, ECO:0000313|Proteomes:UP000002866};
RN   [1] {ECO:0000313|EMBL:CCH58688.1, ECO:0000313|Proteomes:UP000002866}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 /
RC   UCD 77-7 {ECO:0000313|Proteomes:UP000002866};
RX   PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA   Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA   Wolfe K.H.;
RT   "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT   accidents.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
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DR   EMBL; HE806316; CCH58688.1; -; Genomic_DNA.
DR   RefSeq; XP_004178207.1; XM_004178159.1.
DR   AlphaFoldDB; I2GX36; -.
DR   STRING; 1071380.I2GX36; -.
DR   GeneID; 14493469; -.
DR   KEGG; tbl:TBLA_0A08990; -.
DR   eggNOG; KOG1729; Eukaryota.
DR   HOGENOM; CLU_020649_0_0_1; -.
DR   InParanoid; I2GX36; -.
DR   OMA; RHWLYLD; -.
DR   OrthoDB; 38671at2759; -.
DR   Proteomes; UP000002866; Chromosome 1.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd15760; FYVE_scVPS27p_like; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR000306; Znf_FYVE.
DR   InterPro; IPR017455; Znf_FYVE-rel.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR47794; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27; 1.
DR   PANTHER; PTHR47794:SF1; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27; 1.
DR   Pfam; PF01363; FYVE; 1.
DR   SMART; SM00064; FYVE; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR   PROSITE; PS50178; ZF_FYVE; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002866};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00091}.
FT   DOMAIN          563..631
FT                   /note="FYVE-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50178"
FT   REGION          111..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          193..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          259..366
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        193..212
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   730 AA;  81487 MW;  319FA64CCE6C0ADB CRC64;
     MNLDKITERE KTENKDIITQ ETLLANGSTT NMTNYSVQPI INNSEDIGHK KSITSLSSET
     STITFEKQKV TPKTALPHSL LSSSFMARDR LNQKNISANT NINSHFNNAI SNESQQDTNK
     IYPTSSYSES LEASQQSRTP VVQSFKKNNS LQSESANLSN SINLTKPENS KFTDGNNLPK
     EQANLNASVH EINSKSESEI LPNSSNSYYG RAHRNNDELD DETGEKITQQ KELTAQALKR
     LSIFKGNNIT GAFADMTTKN SKSTKSNTSL NSIHSNNDST HYTSPLKLDK KSSNHNLRQQ
     QSIQQHQIFR QSQLVQQPQR QSLQQMQQQT TSFKRPINAT SNASDSSPLR NNNPRKNIFK
     TNFPENGIGL ENSPTMMSIS HTSTTRPQLD KLTVRGPSLR IGSSNSYSHS PLTMNRHGSG
     GPDDYNMGTP RNTFLKAQQK KKSTRQINNP KKPLYIPAVL RDISETNLTN EDLKNPPKLE
     TALSNISDNS PIHASSMQDN QSSRASIHST NSFVKDTLQK FMPSFFSSYN EGSDTDSTIT
     SFETIKGNKS QIMIPKRSHW LPDQKRDGCH YCNKQFTFWE RKHHCRHCGD IFCQQHLCHW
     LYLDEDAQFI IGGGGIGSLC KVCDNCLEIY EKLVIERSTF TTNARSRNTL GGSSSIINKI
     KQSNQESVVS NNTVTQQGIP NKKISRAIDS SYQGIDSQLS DGTGADTNED RTALGSVVGS
     VPANWNWSSF
//