ID I2H7J8_TETBL Unreviewed; 307 AA.
AC I2H7J8;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Protein CCC1 {ECO:0008006|Google:ProtNLM};
GN Name=TBLA0H00590 {ECO:0000313|EMBL:CCH62350.1};
GN ORFNames=TBLA_0H00590 {ECO:0000313|EMBL:CCH62350.1};
OS Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC
OS 10599 / NRRL Y-10934 / UCD 77-7) (Yeast) (Kluyveromyces blattae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX NCBI_TaxID=1071380 {ECO:0000313|EMBL:CCH62350.1, ECO:0000313|Proteomes:UP000002866};
RN [1] {ECO:0000313|EMBL:CCH62350.1, ECO:0000313|Proteomes:UP000002866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 /
RC UCD 77-7 {ECO:0000313|Proteomes:UP000002866};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CCC1 family.
CC {ECO:0000256|ARBA:ARBA00007049}.
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DR EMBL; HE806323; CCH62350.1; -; Genomic_DNA.
DR RefSeq; XP_004181869.1; XM_004181821.1.
DR AlphaFoldDB; I2H7J8; -.
DR STRING; 1071380.I2H7J8; -.
DR GeneID; 14497507; -.
DR KEGG; tbl:TBLA_0H00590; -.
DR eggNOG; KOG4473; Eukaryota.
DR HOGENOM; CLU_038957_0_0_1; -.
DR InParanoid; I2H7J8; -.
DR OMA; HESEPAI; -.
DR OrthoDB; 1357at2759; -.
DR Proteomes; UP000002866; Chromosome 8.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0030026; P:intracellular manganese ion homeostasis; IEA:InterPro.
DR CDD; cd02435; CCC1; 1.
DR InterPro; IPR008217; Ccc1_fam.
DR PANTHER; PTHR31851; FE(2+)/MN(2+) TRANSPORTER PCL1; 1.
DR PANTHER; PTHR31851:SF52; PROTEIN CCC1; 1.
DR Pfam; PF01988; VIT1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002866};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 85..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 307 AA; 32946 MW; F1C8925048B92E85 CRC64;
MTSSLLTNAN KTQGYESIAQ ELGNQDDQHI CMPPQGTINE SVNTDLDRNE FIAPNDNDFF
SPNGGNPMGG QSLLFRVFGK MDPRVISDLI IGLSDGLTVP FALTAGLSSL GDSRLVIAGG
FAELISGAIS MGLGGYLGAK SEADYYHAEV GHQKAGFRED QTSVNHEVED ILLEMNPEFS
PETIVSFVRD LKEHPELMVN FVIRFGKGLE EPAENRQLIS ALTIGGGYLA GGLIPLLPYF
FVAHVGTGLV YSVIVMIITL FWFGYIKTAL AMGDDCSVQK KTLEGLQMIA VGGTAAGAAW
YAVKLLA
//
