ID I2JAW6_9STRE Unreviewed; 274 AA.
AC I2JAW6;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Pur operon repressor {ECO:0000256|ARBA:ARBA00018449};
GN Name=purR {ECO:0000313|EMBL:EIF40118.1};
GN ORFNames=HMPREF1116_1564 {ECO:0000313|EMBL:EIF40118.1};
OS Streptococcus sp. SK140.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1095726 {ECO:0000313|EMBL:EIF40118.1, ECO:0000313|Proteomes:UP000003237};
RN [1] {ECO:0000313|EMBL:EIF40118.1, ECO:0000313|Proteomes:UP000003237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK140 {ECO:0000313|EMBL:EIF40118.1,
RC ECO:0000313|Proteomes:UP000003237};
RA Durkin A.S., McCorrison J., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC family. {ECO:0000256|ARBA:ARBA00008391}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIF40118.1}.
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DR EMBL; AJML01000016; EIF40118.1; -; Genomic_DNA.
DR RefSeq; WP_006146682.1; NZ_AJML01000016.1.
DR AlphaFoldDB; I2JAW6; -.
DR PATRIC; fig|1095726.3.peg.430; -.
DR eggNOG; COG0503; Bacteria.
DR Proteomes; UP000003237; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0045982; P:negative regulation of purine nucleobase metabolic process; IEA:InterPro.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR015265; PuR_N.
DR InterPro; IPR010078; PurR_Bsub.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01743; purR_Bsub; 1.
DR PANTHER; PTHR43864; HYPOXANTHINE/GUANINE PHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR43864:SF2; PUR OPERON REPRESSOR; 1.
DR Pfam; PF00156; Pribosyltran; 1.
DR Pfam; PF09182; PuR_N; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 4..73
FT /note="Bacterial purine repressor N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09182"
FT DOMAIN 107..261
FT /note="Phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00156"
SQ SEQUENCE 274 AA; 30159 MW; 52396DB29F23DCDB CRC64;
MKLRRSDRMV VISNYLINNP YKLTSLNTFA EKYESAKSSI SEDIVIIKRA FEEIEIGHIQ
TVTGAGGGVI FTPSISPLES KTIIEELRDK LSESDRILPG GYIYLSDLLS TPAILKNIGR
IIAKSFMDQK IDAVMTVATK GVPLANAVAN VLNVPFVIVR RDLKITEGST VSVNYVSGSS
DRIEKMFLSK RSLKAGSRVL IVDDFLKGGG TINGMISLLS EFDSELAGVA VFADNAQEDR
EQQFDYKSLL RVTNIDVKNQ QIAVEVGNIF DTEK
//
