ID I2JES6_9GAMM Unreviewed; 234 AA.
AC I2JES6;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Thiol:disulfide interchange protein DsbA {ECO:0000256|ARBA:ARBA00013831};
GN ORFNames=DOK_18400 {ECO:0000313|EMBL:EIF41478.1};
OS gamma proteobacterium BDW918.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales;
OC Spongiibacteraceae.
OX NCBI_TaxID=1168065 {ECO:0000313|EMBL:EIF41478.1, ECO:0000313|Proteomes:UP000003473};
RN [1] {ECO:0000313|EMBL:EIF41478.1, ECO:0000313|Proteomes:UP000003473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BDW918 {ECO:0000313|EMBL:EIF41478.1,
RC ECO:0000313|Proteomes:UP000003473};
RX PubMed=22740675; DOI=10.1128/JB.00678-12;
RA Kim S.M., Cho S.J., Lee S.B.;
RT "Genome Sequence of the Unclassified Marine Gammaproteobacterium BDW918.";
RL J. Bacteriol. 194:3753-3754(2012).
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
CC -!- SIMILARITY: Belongs to the thioredoxin family. DsbA subfamily.
CC {ECO:0000256|ARBA:ARBA00005791}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIF41478.1}.
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DR EMBL; AJMK01000079; EIF41478.1; -; Genomic_DNA.
DR AlphaFoldDB; I2JES6; -.
DR PATRIC; fig|1168065.3.peg.3788; -.
DR eggNOG; COG1651; Bacteria.
DR HOGENOM; CLU_088255_1_0_6; -.
DR Proteomes; UP000003473; Unassembled WGS sequence.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd03019; DsbA_DsbA; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR001853; DSBA-like_thioredoxin_dom.
DR InterPro; IPR023205; DsbA/DsbL.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR35891; THIOL:DISULFIDE INTERCHANGE PROTEIN DSBA; 1.
DR PANTHER; PTHR35891:SF2; THIOL:DISULFIDE INTERCHANGE PROTEIN DSBA; 1.
DR Pfam; PF01323; DSBA; 1.
DR PIRSF; PIRSF001488; Tdi_protein; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Periplasm {ECO:0000256|ARBA:ARBA00022764};
KW Reference proteome {ECO:0000313|Proteomes:UP000003473};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..234
FT /note="Thiol:disulfide interchange protein DsbA"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003662089"
FT DOMAIN 27..228
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT DISULFID 80..83
FT /note="Redox-active"
FT /evidence="ECO:0000256|PIRSR:PIRSR001488-1"
SQ SEQUENCE 234 AA; 25701 MW; 2595E77DBBF72442 CRC64;
MFKKFIPLVS VFSFLLMVSA CSDGAEPAAP AKAPASTAVN TADTAERIAS SGERYIRVAQ
PVRTANPQKI EVTEVFWYGC SHCFDFDPML EAWAKQLPAD VEFRRSPAMW NELMVVHAKA
FYTAEALGVI DQLHTPLFNA INVDRNPLRD SAAIEKLFLA HSDVDAEKFR KTFDSFGVNS
QVKQADARAR AYGIAGTPEL IVNGKYRVTG RSAGGKAEML KVAEELIAKE RAAK
//
