ID I2JI22_9GAMM Unreviewed; 631 AA.
AC I2JI22;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=Glycerol-3-phosphate acyltransferase {ECO:0000256|ARBA:ARBA00013432};
DE EC=2.3.1.15 {ECO:0000256|ARBA:ARBA00013113};
GN ORFNames=DOK_13047 {ECO:0000313|EMBL:EIF42624.1};
OS gamma proteobacterium BDW918.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales;
OC Spongiibacteraceae.
OX NCBI_TaxID=1168065 {ECO:0000313|EMBL:EIF42624.1, ECO:0000313|Proteomes:UP000003473};
RN [1] {ECO:0000313|EMBL:EIF42624.1, ECO:0000313|Proteomes:UP000003473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BDW918 {ECO:0000313|EMBL:EIF42624.1,
RC ECO:0000313|Proteomes:UP000003473};
RX PubMed=22740675; DOI=10.1128/JB.00678-12;
RA Kim S.M., Cho S.J., Lee S.B.;
RT "Genome Sequence of the Unclassified Marine Gammaproteobacterium BDW918.";
RL J. Bacteriol. 194:3753-3754(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=an acyl-CoA + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-
CC phosphate + CoA; Xref=Rhea:RHEA:15325, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:57597, ChEBI:CHEBI:57970, ChEBI:CHEBI:58342; EC=2.3.1.15;
CC Evidence={ECO:0000256|ARBA:ARBA00000510};
CC -!- PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-
CC diacylglycerol from sn-glycerol 3-phosphate: step 1/3.
CC {ECO:0000256|ARBA:ARBA00004765}.
CC -!- SIMILARITY: Belongs to the GPAT/DAPAT family.
CC {ECO:0000256|ARBA:ARBA00007937}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIF42624.1}.
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DR EMBL; AJMK01000066; EIF42624.1; -; Genomic_DNA.
DR AlphaFoldDB; I2JI22; -.
DR PATRIC; fig|1168065.3.peg.2680; -.
DR eggNOG; COG2937; Bacteria.
DR HOGENOM; CLU_015407_1_0_6; -.
DR OrthoDB; 335193at2; -.
DR UniPathway; UPA00557; UER00612.
DR Proteomes; UP000003473; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004366; F:glycerol-3-phosphate O-acyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0102420; F:sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity; IEA:UniProtKB-EC.
DR GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd07993; LPLAT_DHAPAT-like; 1.
DR InterPro; IPR022284; GPAT/DHAPAT.
DR InterPro; IPR045520; GPAT/DHAPAT_C.
DR InterPro; IPR041728; GPAT/DHAPAT_LPLAT.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR12563:SF17; DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE; 1.
DR PANTHER; PTHR12563; GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR Pfam; PF19277; GPAT_C; 1.
DR PIRSF; PIRSF000437; GPAT_DHAPAT; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:EIF42624.1}; Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000003473};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EIF42624.1}.
FT DOMAIN 120..247
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 631 AA; 71064 MW; D96965A5F7B2CE9A CRC64;
MKEKDIEQDE RDLSQHAGKQ VSEASDSSIT MGKKAIVSKI LGSSRVQNAL RELAVKEGLS
QSEAHSRARR SLQSLVAVQK PLFTTLFDRV LAPMHTNAWT VDVDQESLRR LEVLSRDNML
VFLPTHRSYA DPFILTQLIS SSALPRNYIL GGDNIGFWPM GSVVRRSGAI LIRRSFGDDR
VYKLMIKEYL AYLARSGGNL EWYMEGGRSR TGKLRPPMYG LLRYLGQALS VESRKSVILV
PVAITYDQLH EIWGMAAEEA GNAKKAKEGL PWLANYARMQ SKWIGTAYVR FGELMSLTEA
MHPDSKNPST IEKVAIEVFQ RINKVTPVTG PALATLALLA VRNRALTLPE ITHLVSPLLD
YARRRALPTE VVDELDNHSG IEDALSSLAK ADVLDCYKGG LEPIYNIRAG SHNIAAYYRN
SAIHWFINRA ILEVTLLHTS HINNGDENIF DQGWDDAHAL RDVLKFEFFF SEKNKFKEEM
REEALILDAD FFAKVQRAEE RRNMLYQAPF LMAHRVLMPF LEAYVIVAEL MASKGGGTIS
DESLFIAECL SVGRQWVLQY KIRSPESLSQ ELFKNALKLA KNRDLLEQRL GLHEDRLALK
DYLHSVVAAL ANVESLDLER CANSQEGGVN E
//
