ID I2JQ69_9GAMM Unreviewed; 737 AA.
AC I2JQ69;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Molybdopterin oxidoreductase {ECO:0000313|EMBL:EIF45121.1};
GN ORFNames=DOK_00240 {ECO:0000313|EMBL:EIF45121.1};
OS gamma proteobacterium BDW918.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales;
OC Spongiibacteraceae.
OX NCBI_TaxID=1168065 {ECO:0000313|EMBL:EIF45121.1, ECO:0000313|Proteomes:UP000003473};
RN [1] {ECO:0000313|EMBL:EIF45121.1, ECO:0000313|Proteomes:UP000003473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BDW918 {ECO:0000313|EMBL:EIF45121.1,
RC ECO:0000313|Proteomes:UP000003473};
RX PubMed=22740675; DOI=10.1128/JB.00678-12;
RA Kim S.M., Cho S.J., Lee S.B.;
RT "Genome Sequence of the Unclassified Marine Gammaproteobacterium BDW918.";
RL J. Bacteriol. 194:3753-3754(2012).
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIF45121.1}.
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DR EMBL; AJMK01000001; EIF45121.1; -; Genomic_DNA.
DR AlphaFoldDB; I2JQ69; -.
DR PATRIC; fig|1168065.3.peg.54; -.
DR eggNOG; COG0243; Bacteria.
DR HOGENOM; CLU_000422_13_3_6; -.
DR Proteomes; UP000003473; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR PANTHER; PTHR43742:SF6; OXIDOREDUCTASE YYAE-RELATED; 1.
DR PANTHER; PTHR43742; TRIMETHYLAMINE-N-OXIDE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00490; MOLYBDOPTERIN_PROK_2; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000003473}.
FT DOMAIN 14..71
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 737 AA; 80143 MW; 335D517A4D0C2DAC CRC64;
MIAPIMNNKR SSSPRIDKKI FCGVCESSCG LVATIKDDDL IKLRPDPDHP NSKGFACSKG
LAFGAVRDDS DRVLHPLKRT DDGSFVAVSW EQALDEIGER LNAIIKVHGR ESIGLYQGNS
VAWNFGAFLN LFGMAGALKT KHLYSAASID INGYWLVSQL LYGSNFLNPV PDIARTDFML
CIGANPVVSH GSMANIGRFR DTMLGVTARG GRVVVIDPRR SETAELFEHL PIRPNGDAWL
LAAMLKVIFD EGLADLAALQ RQTSGSEIIT DLLAPVSLAQ ASDAAGIPVA DIQQLARDFA
AAPSACAYGR CGMSIGPFAT LSKYLLDVLN IATGNLDREG GWCFARPFID LEALMHQLKS
TGYDRWRTRV DGFPEVAGTA PVVSIPREIT TPGKGQLRAM MVIGANPATS SPAAGELRDA
FKQLDLLISQ DIYITETSRM ADYILPPTTW LEREGFPIFT QSHSGVPHAQ WVGPTLKARG
DVRDDAWIMD EISKRIGIVP ADFPGAQLLG KLGLRPSPSF LMDVGLRTGP EGDWFGLRPS
GLSRKKLLNN DGAIKLANGL PTGVLNKRMF TKDKKVNLDH AVFRTEMARL LASSFAQDEN
YPLSLISQRE LRSQNTWLHN ISKLVVADRV QRLRIHPTDA ARYGIEEGDP VEISSPYGQI
RVPEARISDE MMPGSLALPH GWGHEGGWQR AVAVGGAGYN QLTTNRADSA DLPSGNATVN
GISVRIRSLR DVVEMAS
//
