ID I3ICL9_9GAMM Unreviewed; 484 AA.
AC I3ICL9;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=tRNA and rRNA cytosine-C5-methylase {ECO:0000313|EMBL:EIK45804.1};
GN ORFNames=O59_001443 {ECO:0000313|EMBL:EIK45804.1};
OS Cellvibrio sp. BR.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales;
OC Cellvibrionaceae; Cellvibrio.
OX NCBI_TaxID=1134474 {ECO:0000313|EMBL:EIK45804.1, ECO:0000313|Proteomes:UP000003395};
RN [1] {ECO:0000313|EMBL:EIK45804.1, ECO:0000313|Proteomes:UP000003395}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BR {ECO:0000313|EMBL:EIK45804.1,
RC ECO:0000313|Proteomes:UP000003395};
RA Peng Y.Y., Li N.Z., Xia T., Qiu R.R.;
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RsmB/NOP family. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIK45804.1}.
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DR EMBL; AICM01000002; EIK45804.1; -; Genomic_DNA.
DR RefSeq; WP_007640622.1; NZ_JH668201.1.
DR AlphaFoldDB; I3ICL9; -.
DR STRING; 1134474.O59_001443; -.
DR PATRIC; fig|1134474.3.peg.1293; -.
DR eggNOG; COG0144; Bacteria.
DR HOGENOM; CLU_005316_0_2_6; -.
DR Proteomes; UP000003395; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR InterPro; IPR023267; RCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR22807; NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR22807:SF77; SUN PROTEIN; 1.
DR Pfam; PF01189; Methyltr_RsmB-F; 1.
DR PRINTS; PR02008; RCMTFAMILY.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01023};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU01023};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01023};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01023}.
FT DOMAIN 209..484
FT /note="SAM-dependent MTase RsmB/NOP-type"
FT /evidence="ECO:0000259|PROSITE:PS51686"
FT ACT_SITE 436
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 333
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 383
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ SEQUENCE 484 AA; 54173 MW; 25674DAB48C53166 CRC64;
MQNPTEHNTV SPHNSTVTVQ YEDSRLVPLW RAWLEVAGTM PLDKWIKTSV RQFAHSGPTS
MPEYDEIKKH NKFKPTKTQA DHANAEAIDT ASLSLAMFSA LRFQQLASGL EFAYRASLQN
PEHVMDWSEW DAGWQARDLQ GIAPVAFWYW IQLRVNGDQP KKNQAQLRDA EARRSFFKKV
MAEATFANLP VLLLWQGLRP QWSELLKARQ QASGWSDKTL EDFIAQQIST PPLWLRVQKN
ASAEAVYNSL QQQGVKVSLS EQGLAAQGGV GIHTTDAYKS GLVEIQDLAS QQIAATVAAK
PGQKVWDACA GAGGKTLAIA AQMNNKGAVF ATDLHAYKLD ELKRRAKRAD VFNVRVFTWE
GSEPLRLPKE AAQQQGFDWV LIDAPCSSAG TWRRNPDARW RFDPADTREL VHLQQQLLTN
AAPAVRVGGR LVYATCSWQV SENEQQVEWF LAQHPQFALE SQKILGAPAI DSDTMFVAVL
IRQS
//
