ID I3IRE1_9BACT Unreviewed; 487 AA.
AC I3IRE1;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GAB64286.1};
GN ORFNames=KSU1_D0977 {ECO:0000313|EMBL:GAB64286.1};
OS Candidatus Jettenia caeni.
OC Bacteria; Planctomycetota; Candidatus Brocadiia; Candidatus Brocadiales;
OC Candidatus Brocadiaceae; Candidatus Jettenia.
OX NCBI_TaxID=247490 {ECO:0000313|EMBL:GAB64286.1, ECO:0000313|Proteomes:UP000002985};
RN [1] {ECO:0000313|EMBL:GAB64286.1, ECO:0000313|Proteomes:UP000002985}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22673575; DOI=10.1016/j.febslet.2012.04.041;
RA Hira D., Toh H., Migita C.T., Okubo H., Nishiyama T., Hattori M.,
RA Furukawa K., Fujii T.;
RT "Anammox organism KSU-1 expresses a NirK-type copper-containing nitrite
RT reductase instead of a NirS-type with cytochrome cd1.";
RL FEBS Lett. 586:1658-1663(2012).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAB64286.1}.
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DR EMBL; BAFH01000004; GAB64286.1; -; Genomic_DNA.
DR AlphaFoldDB; I3IRE1; -.
DR STRING; 247490.KSU1_D0977; -.
DR eggNOG; COG1032; Bacteria.
DR OrthoDB; 9762608at2; -.
DR Proteomes; UP000002985; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF12; BLL1977 PROTEIN; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Reference proteome {ECO:0000313|Proteomes:UP000002985}.
FT DOMAIN 8..144
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 186..412
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 487 AA; 56650 MW; E8FFA5E03AAC8EA3 CRC64;
MNILLLSMPD CAPHFNANRW KPPNLAISSI AGNIEGHNVY LADLILRRTR IAETIRELLL
QYQPDIVGLS AMSFQFATAK RIADLVKSLK KDTKTVLGGY HATLMYHEMC ESDDSGPFDF
IIRGEGDLCF NELLEAIDGK RSLESIPGIS FRVDNYFIHN QARPLEDLTK IKIPNRSQRI
WKGYQYYGFT LDIVESSRGC VMPCNFCSMD KMYGKTFRRF SIERILLDIA NAKQNGANFI
IFSDDNFTLD IKGFESLCDA ITEAGHNDIR YIIQASSMGI TSSDTLIEKM AKAGFRIVFL
GIENASEENL RLLKKGNIIE RTKLAVKRLH EYNIMIVGGM IIGNPNDKEE DIARNYEFFV
NLQIDFFADQ ILTPYPKTGM REELLNMGLV TNKYDYSRYN CFWANIKTNY LEPEDIQFLR
WKYNRKYANY ICTTPAFIKN YPLAYYYRQY FRRPFFKIKN RLFQNSISEK ELYKRDMERA
EAMNKFF
//
