ID I3ITV2_ORENI Unreviewed; 1046 AA.
AC I3ITV2;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Myosin binding protein C, slow type {ECO:0000313|Ensembl:ENSONIP00000000041.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000000041.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000000041.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; I3ITV2; -.
DR Ensembl; ENSONIT00000000041.2; ENSONIP00000000041.2; ENSONIG00000000034.2.
DR GeneTree; ENSGT00940000158254; -.
DR HOGENOM; CLU_006405_1_1_1; -.
DR Proteomes; UP000005207; Linkage group LG17.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 9.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR InterPro; IPR040849; MyBP-C_THB.
DR PANTHER; PTHR13817:SF27; MYOSIN-BINDING PROTEIN C, SLOW-TYPE; 1.
DR PANTHER; PTHR13817; TITIN; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 5.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF18362; THB; 1.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 26..130
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 313..399
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 404..486
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 495..595
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 602..696
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 698..793
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 839..935
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 951..1035
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1046 AA; 117323 MW; CC325EB65FA39954 CRC64;
MGRKDSVWSL GEGQAPDELE KPVDNPPLST LLIESPQSGT VTVGGDITFV AKVEAKDLLR
KPTVKWFKGK WMDLASKTGK HLQLKETFDR VTKVHTFEMH IIKAKDNYAG NYRCEVNYKD
KFDSCSFDLE VKEAGTGSQN IDIRSAFKRS SEGQEDAGEL DFSGLLKHRE HKQQDDTPEV
DVWEILKNAR PDQYEKIAFM YGITDLRGLL KRLKKMPKEE KKLEAFAKKL EPAYQVDKGG
KIRLVVDLAD PTVELKWYKN GQEIRPSPKY IFEHKGTQRI MVINNCSAND DAAYSVVAGD
EKCSTELFVK ELPVKIVKGL EPVKTTVNER IELECEVSEE GAQVKWLKNG VEVPTGVRSR
YRVKCEGTKH FLVIDDASRD DTGTYSIMAS GGTSEAHIQV DLKPLKVYQD LQDMTVLLGQ
PIKLHCEIYP GNVPGRWYRN GQLIQPSDRI NIIHRNKVHR LEIAASSLHD AGDYTFVPEG
YSQSLSAKIH IIDPPRVHLD SLNFPDNTVT VVAGNKLRLE IPISGEPAPR VVWMKGERVR
PFDSVILESG HRIHAETYSD HTSLTIEVTE REDTGNYKIV LQNEAGEATA SVKIKVVDIP
DPPEAPLVPE VGGDWCSMTW EPPKYDGGSP ILGYYVERKK KQSSRWMRLN FDLIKETTFE
PKKMIEGVPY EVRIFAVNAI GVSKPSEPSK AFTPLGDEPT MLVVDDVTDT TVTVKWRPPE
TIGAAGLDGY LVEYCVEGTN DWVISNKELT EKTRYTITGL SPGCKILVRV KAVNAAGASA
PLHYICSAVT LIRNTDCDSI IFIRKAERSH SGKYDMTVQV ENHVDTAILD IQIVDLPGPP
QCVNIEDVWG GNVALVWTPP KDNGNAPITG YTIQKADKKT MEWFTCIEHY HRNCITITEL
VVGNEYFFRI FSENMCGLSE TATQTKKSAL IVKEGTMKTQ EYNDHDFKEA PKFTQPLINT
FAVAGYNTTL NCSVRANPRP KVIWMKNKIT IIDDPRYRMF SSQGVCTLEI RKPSPYDGGM
YTCKAINELG EAQVDCKLEV KGQCGP
//
