ID I3IUX1_ORENI Unreviewed; 251 AA.
AC I3IUX1;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Cationic trypsin {ECO:0000313|Ensembl:ENSONIP00000000411.2};
GN Name=LOC102077969 {ECO:0000313|Ensembl:ENSONIP00000000411.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000000411.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Ensembl:ENSONIP00000000411.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase S1 family.
CC {ECO:0000256|ARBA:ARBA00007664}.
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DR RefSeq; XP_005464035.2; XM_005463978.3.
DR AlphaFoldDB; I3IUX1; -.
DR STRING; 8128.ENSONIP00000000411; -.
DR Ensembl; ENSONIT00000000410.2; ENSONIP00000000411.2; ENSONIG00000000326.2.
DR GeneID; 102077969; -.
DR KEGG; onl:102077969; -.
DR eggNOG; KOG3627; Eukaryota.
DR GeneTree; ENSGT00390000009571; -.
DR HOGENOM; CLU_006842_1_5_1; -.
DR InParanoid; I3IUX1; -.
DR OMA; TWINQNA; -.
DR OrthoDB; 4198500at2759; -.
DR TreeFam; TF351693; -.
DR Proteomes; UP000005207; Unplaced.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR PANTHER; PTHR24276:SF91; AT26814P-RELATED; 1.
DR PANTHER; PTHR24276; POLYSERASE-RELATED; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..251
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025565121"
FT DOMAIN 27..251
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
SQ SEQUENCE 251 AA; 27881 MW; 5E5A96C302364D95 CRC64;
MAHLTFLLLL LWVAVTVSTV VDLQKRIYGG TDCNQNERQY HVSLTLYADG SCSHCGGSLI
RNQWILTAAH CKSRPMFAVV GVHAGQRNVQ RIEENNIITH QHDDIMLVKL PNPTAGIPTV
PYCPNINDDP TIGNNVQVAG HSTHIIDQQG FIVPDFPSNL KCATMDVVNC DNPFWNTFYQ
QNPYLPHVPQ QNRLCLQRHG VDVRPGDSGG GVIHRNNLYG VIVATGLNVC TCQTLSIRVC
PYMTWINQNA V
//
