ID I3J1Y2_ORENI Unreviewed; 1026 AA.
AC I3J1Y2;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Contactin-3 {ECO:0000313|Ensembl:ENSONIP00000002872.1};
GN Name=LOC100703160 {ECO:0000313|Ensembl:ENSONIP00000002872.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000002872.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000002872.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Interacts with PTPRG. {ECO:0000256|ARBA:ARBA00038703}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. Contactin
CC family. {ECO:0000256|ARBA:ARBA00009812}.
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DR RefSeq; XP_005478280.1; XM_005478223.3.
DR AlphaFoldDB; I3J1Y2; -.
DR STRING; 8128.ENSONIP00000037279; -.
DR Ensembl; ENSONIT00000002873.2; ENSONIP00000002872.1; ENSONIG00000002300.2.
DR GeneID; 100703160; -.
DR KEGG; onl:100703160; -.
DR CTD; 100000688; -.
DR eggNOG; KOG3513; Eukaryota.
DR GeneTree; ENSGT00940000164703; -.
DR HOGENOM; CLU_005756_0_0_1; -.
DR OrthoDB; 3073820at2759; -.
DR TreeFam; TF351103; -.
DR Proteomes; UP000005207; Linkage group LG20.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF18; CONTACTIN 4-RELATED; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF07679; I-set; 4.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 4.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 6.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 4.
DR PROSITE; PS50835; IG_LIKE; 6.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1026
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003672072"
FT DOMAIN 29..120
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 125..216
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 230..312
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 321..405
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 411..500
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 502..588
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 601..699
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 704..801
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 806..900
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 901..998
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 1026 AA; 112231 MW; 3D5206C5B35FF36F CRC64;
MTLPWKQLLL LSIIDCLTDC LDSGSFHGPR WRMEPGDLFI PIDSIEEEAT LTCDAKGTPS
PQYRWSLNGT LINLGLDRRR RLSGGNLIIS SLDRYQDVGM YQCMAYNTVG AILSRRASLQ
FAYLDHFKVH TRSAVSVREG QGVVLLCGTP TSSGDLTYAW IFNEYPYFVQ QDNRRFVSQQ
TGNLYIAKVE PSDVGNYTCV VMNSITKGKV QSSPTSLILR TDGVMGEYEP KIEVNFPDNV
PAAKGSTVTL ECFALGNPVP EITWRRANGV PFPSKVKMKY SNAVLEIPSF QQDDTGGYEC
VAENKMGKNT VSGRLAFYAK PQWVQTMKDT ALAIEERLYW ECRANGRPKP SYTWLKNGQQ
LLSEDRIHVE DGVLSVSALT LSDAGMYQCV AENKHGVIYF AAELMVLASP PDFTGNLLRA
LLKAKAGTTV TLECKPQAYP IASILWKKGN LPIHTNDRIT LSPDGTLRLA NVSKSDAGSY
TCFARNRFGM SSTTGRLLVT DPTRIIQGPV DTEIIVGESI VLPCQVASDP VLDVSFSWAF
NGQLIAKGDG HFEFVGGRTA GDLMIRNIQL YHAGKYICVV DTDVESLSAV AVLIVKGPPS
PPDSVTVEEV TDSTAQLAWS PGRDNGSPIT NYLIQTRTPF TVGWQRVNTV PEIIDGNTLT
ATVVDLNAWV EYDFRVLAKN SVGVGEPSPV SVKTRTEDAV PDAVPGDVGG GGGSRYELVI
TWEPVPEELQ NGESFGYIIA FRAFGEASWT HVATSAPGAS RYVYRNDSIA PFSPFHVKVG
TYNSKGQGPF SPVVTIYSAE TEPSEKPAGV RARSVSASEI EVNWQALSFI PERVLGYEVA
YWEDDTKPET MGKVRVPWNQ TSATVSGLAG NTQYFLTVSA FNTAGTSPFL PAINVTTKKP
PPSQPPMNVG WNLMGSQLSV YWEPVVAMES ESDVLGYQLS YQRQRHKEVI TLTTVNATAE
LTLPEDDEEY IIFVQTLSEG GLGPASDPIR IHQLSMSARG SRACSVEISP LSLFLTIAVS
SFRSSL
//
