ID I3JA91_ORENI Unreviewed; 214 AA.
AC I3JA91;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Sorting nexin-10A {ECO:0000313|Ensembl:ENSONIP00000005781.2};
GN Name=LOC100705689 {ECO:0000313|Ensembl:ENSONIP00000005781.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000005781.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000005781.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR RefSeq; XP_003448953.1; XM_003448905.4.
DR RefSeq; XP_005453879.1; XM_005453822.3.
DR RefSeq; XP_005453880.1; XM_005453823.3.
DR RefSeq; XP_005453881.1; XM_005453824.3.
DR AlphaFoldDB; I3JA91; -.
DR STRING; 8128.ENSONIP00000005781; -.
DR Ensembl; ENSONIT00000005785.2; ENSONIP00000005781.2; ENSONIG00000004590.2.
DR GeneID; 100705689; -.
DR KEGG; onl:100705689; -.
DR CTD; 403027; -.
DR eggNOG; KOG2527; Eukaryota.
DR GeneTree; ENSGT00940000156007; -.
DR HOGENOM; CLU_057172_4_0_1; -.
DR InParanoid; I3JA91; -.
DR OMA; TEFISIC; -.
DR OrthoDB; 5475877at2759; -.
DR TreeFam; TF332117; -.
DR Proteomes; UP000005207; Linkage group LG22.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
DR GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0070121; P:Kupffer's vesicle development; IEA:Ensembl.
DR GO; GO:0070986; P:left/right axis specification; IEA:Ensembl.
DR CDD; cd06898; PX_SNX10; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR043544; SNX10/11.
DR PANTHER; PTHR46209; PX DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46209:SF2; SORTING NEXIN-10; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT DOMAIN 13..130
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
SQ SEQUENCE 214 AA; 24647 MW; C04F9B9AB13EE5BE CRC64;
MDTILDNFSN TEFIRVCVQD PRLHKDDRWH THVDYEICLH TNSMCFRKKT SSVRRRYSEF
VWLRHCLEQN AFIIDLPKLP PWNPFFSLKN TEQVIQRIKG LQKFLEIVLH TPLLLSDSRL
HLFLQSDLSI TKIAKCAVGK TRYTVAEAIQ RSRTGCIRSE EKVSCDSDCE STSSSGLGLS
VDTSERGSPI FFQSDGEPEP FCSFSETTSP LTEY
//
