ID I3JI60_ORENI Unreviewed; 407 AA.
AC I3JI60;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Trophoblast glycoprotein {ECO:0000313|Ensembl:ENSONIP00000008554.2};
GN Name=LOC100697007 {ECO:0000313|Ensembl:ENSONIP00000008554.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000008554.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000008554.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_003452158.1; XM_003452110.4.
DR AlphaFoldDB; I3JI60; -.
DR STRING; 8128.ENSONIP00000008554; -.
DR Ensembl; ENSONIT00000008559.2; ENSONIP00000008554.2; ENSONIG00000006775.2.
DR GeneID; 100697007; -.
DR KEGG; onl:100697007; -.
DR eggNOG; KOG0619; Eukaryota.
DR GeneTree; ENSGT00940000154868; -.
DR HOGENOM; CLU_064866_0_0_1; -.
DR InParanoid; I3JI60; -.
DR OMA; EMASHTF; -.
DR OrthoDB; 2968652at2759; -.
DR TreeFam; TF351115; -.
DR Proteomes; UP000005207; Linkage group LG11.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24364; LP06937P; 1.
DR PANTHER; PTHR24364:SF22; TROPHOBLAST GLYCOPROTEIN-LIKE PRECURSOR; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 2.
DR SMART; SM00369; LRR_TYP; 5.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..407
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025353644"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 239..290
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
FT REGION 375..407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 407 AA; 44818 MW; 24C185A21CCC59E3 CRC64;
MCFSAVFVFL GILFCALCRC LECPFGCECF AVIRTVKCVS KDLLTAPENI PGYARTVIIT
GNNIHQIGPS SFTEPENITN IILSNNRLTE MASHTFSSLV NLRFLDLSGN QLALIHPEAL
SIPGSPLQEL NLSQSLYNFT ALTDLTTALR WGGLAGLLRL DLSGNKLALL PPGMFSHLPN
LQQLFLTNNS LVAVYSGTFS GMNHLEVLDL THNTFSTFRT DALLELDKLG DIRILLGNNP
YTCSCEINEF VAWLNKSRAK VDVDAVRCAS PGTLTDARLR GLSIQDIGCV VPVLAEVADL
TLQTSYVFLG LVLGLVGMVF LFVLYLNRKG MKKWINEMRD ACRDVLEGYH YRYEIDSDPR
LGHISADSRR AQRQSGISLS QQLPSDTSVA PTKTQVRQLT ISPPVNL
//
