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Database: UniProt
Entry: I3JQZ6_ORENI
LinkDB: I3JQZ6_ORENI
Original site: I3JQZ6_ORENI 
ID   I3JQZ6_ORENI            Unreviewed;       667 AA.
AC   I3JQZ6;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   25-OCT-2017, entry version 36.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSONIP00000011290};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000011290, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Ensembl:ENSONIP00000011290}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2012) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSONIP00000011290, ECO:0000313|Proteomes:UP000005207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=25186727; DOI=10.1038/nature13726;
RA   Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA   Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J.,
RA   Johnson J., Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J.,
RA   Amemiya C., Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A.,
RA   Bloomquist R., Carleton K.L., Conte M.A., D'Cotta H., Eshel O.,
RA   Gaffney L., Galibert F., Gante H.F., Gnerre S., Greuter L., Guyon R.,
RA   Haddad N.S., Haerty W., Harris R.M., Hofmann H.A., Hourlier T.,
RA   Hulata G., Jaffe D.B., Lara M., Lee A.P., MacCallum I., Mwaiko S.,
RA   Nikaido M., Nishihara H., Ozouf-Costaz C., Penman D.J., Przybylski D.,
RA   Rakotomanga M., Renn S.C., Ribeiro F.J., Ron M., Salzburger W.,
RA   Sanchez-Pulido L., Santos M.E., Searle S., Sharpe T., Swofford R.,
RA   Tan F.J., Williams L., Young S., Yin S., Okada N., Kocher T.D.,
RA   Miska E.A., Lander E.S., Venkatesh B., Fernald R.D., Meyer A.,
RA   Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA   Di Palma F.;
RT   "The genomic substrate for adaptive radiation in African cichlid
RT   fish.";
RL   Nature 513:375-381(2014).
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSONIP00000011290}.
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DR   EMBL; AERX01034241; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AERX01034242; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AERX01034243; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AERX01034244; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AERX01034245; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AERX01034246; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 8128.ENSONIP00000011290; -.
DR   Ensembl; ENSONIT00000011299; ENSONIP00000011290; ENSONIG00000008979.
DR   eggNOG; KOG1419; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00550000074513; -.
DR   OMA; RMYTSRK; -.
DR   OrthoDB; EOG091G02ZT; -.
DR   TreeFam; TF315186; -.
DR   Proteomes; UP000005207; Unplaced.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR   InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR   InterPro; IPR028325; VG_K_chnl.
DR   PANTHER; PTHR11537; PTHR11537; 3.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF03520; KCNQ_channel; 2.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01459; KCNQCHANNEL.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005207};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00788393, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00793138,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00789957,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268}.
FT   TRANSMEM     70     92       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     98    123       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    144    164       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    212    231       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    238    257       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    269    295       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       72    295       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      415    553       KCNQ_channel. {ECO:0000259|Pfam:PF03520}.
FT   DOMAIN      573    638       KCNQ_channel. {ECO:0000259|Pfam:PF03520}.
SQ   SEQUENCE   667 AA;  75206 MW;  D99665C4F7C2F466 CRC64;
     MNNAGDGLLS APSAAGATGS DNARGKQGAR LSLLGKPLLY STQSGRRNVR YRRLQNYLYN
     VLERPRAWAF IYHAFVFVLV FSCLVLSVFS TIPAHQEFSS YCLLILEFVM IVVFGLEFII
     RIWSAGCCCR YRGWQGRLRF ARKPFCVIDI IVLIASVAVV SAGSQGNIFA TSVLRSLRFL
     QILRMVRMDR RGGTWKLLGS VVYAHSKELV TAWYIGFLVL IFSSFLVYLV ENKFNNEFAT
     YADALWWGTI TLTTIGYGDK TPKTWTGRML SAGFALLGIS FFALPAGILG SGFALKVQEQ
     HRQKHFEKRR NPAAYLIQAA WRYYSTDSTR PYLDATWRHY ESLLPIHSYL TLCDRCQNKF
     LKSSVQSESS LVFTKEQGES TTSQKLSFKE RVRMASPRGQ SIKNRQTSSV NDRRSPVADA
     GTEGTSPAKV QKSWSFNDRT RFRPSLRLKS QSRSTTDADS NITAEDGFDE KGCHCDISVE
     DLQPSVKSVI RAVRIMKFHV AKKKFKETLR PYDVKDVIEQ YSAGHLDMLC RIKSLQTRLD
     MIVGPQPLSS RAKAFSSPSL SVYYSQGRKN STQGVDQILG KGQIPLDKKI RDKLLSDGDI
     LEDMSMLGRV CKVERQVQSI ESKLDSLLDI YRQVLRKGSS SALTLSSLPL FELEQTSDYH
     SSVFSKD
//
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