ID   I3JW60_ORENI            Unreviewed;       776 AA.
AC   I3JW60;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 2.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=MTSS1-like protein {ECO:0000313|Ensembl:ENSONIP00000013105.2};
GN   Name=LOC100697954 {ECO:0000313|Ensembl:ENSONIP00000013105.2};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000013105.2, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Proteomes:UP000005207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Broad Institute Genome Assembly Team;
RG   Broad Institute Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSONIP00000013105.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_005471136.1; XM_005471079.2.
DR   AlphaFoldDB; I3JW60; -.
DR   Ensembl; ENSONIT00000013115.2; ENSONIP00000013105.2; ENSONIG00000010426.2.
DR   GeneID; 100697954; -.
DR   CTD; 560413; -.
DR   GeneTree; ENSGT00950000183156; -.
DR   HOGENOM; CLU_004805_2_1_1; -.
DR   InParanoid; I3JW60; -.
DR   OMA; NSAMHEV; -.
DR   OrthoDB; 3875239at2759; -.
DR   Proteomes; UP000005207; Linkage group LG7.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR   CDD; cd07643; I-BAR_IMD_MIM; 1.
DR   CDD; cd22060; WH2_MTSS1; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR013606; I-BAR_dom.
DR   InterPro; IPR030127; MTSS1/MTSS2.
DR   PANTHER; PTHR15708; ACTIN BUNDLING/MISSING IN METASTASIS-RELATED; 1.
DR   PANTHER; PTHR15708:SF8; PROTEIN MTSS 2; 1.
DR   Pfam; PF08397; IMD; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   PROSITE; PS51338; IMD; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT   DOMAIN          1..249
FT                   /note="IMD"
FT                   /evidence="ECO:0000259|PROSITE:PS51338"
FT   REGION          253..328
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          377..457
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          475..512
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          555..619
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          724..743
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        377..412
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        570..604
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        728..743
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   776 AA;  83723 MW;  3FA5B74BCDDB2A5D CRC64;
     MESVEKECGA LGGLFQAIVN DMKSSYPVWE DFSAKATKLH SQLRTTILAA VAFLDAFQKV
     ADMATNSRGA TRDIGSALTR MCMRHRSIEA KLRHFTNALM EGLVTPLQDR IEEWKKTANQ
     LDKDHAKEYK RSRQEIKRKS LDTIKLQKKA RKGRGNLRPQ LDSAMQDVSD LYLLMEETEK
     QAVRRALLEE RGRYCSFINL LQPVVNIEIA MLGEITHLQA IVDDLTLLTE DPHKLPPASE
     QVIRDLKGSD YSWSYQTPPS SPSSTGSRKS SMCSLLQMPS SGAHRLSSVS SHDSGFVSQD
     ANTHSKPPSP MPSDITSQKS TSSASSEASE TCQSVSECNS PTAFGSCSSF GTFRPAFSHT
     GTIRPLSVIL PASPTFNHSP GSNTPSPTSK VPSWKDWAKS SSCEPSLAST PQRRRESVDK
     MRELEAPPSP QGYSGMQADE PHRVRSGPGT IAAKHGEPLS PAASTLAMVL TRGLSMEQQK
     SSRDSLQYSS GYSTQTNTPS CSEDTIPSQG SDYECYSLNG DADSEGQVDF DKSSTIPRHS
     NIAQSYRRMI QTKRPASTAG LPAGKTVQGT PNGAGGSSAG AIASGTATIR RTPSSKTGVR
     RTPSTSGPIP IRPPIVPVKT PTVPNSPGYT SPSHHSAGSE EFLYGDDLSA SDNMRAPPKR
     MSLPDTSWGC GRGVDSTVYE QQALGMAVQS VEEDPMLAAN RHSLVEKIGE LAASAHALGE
     GQFPFPSSLS GDPAQFAPQG ASSVSQEDVD MLVSIRRGVK LRKTVTDDRS APRILR
//