ID I3JXD7_ORENI Unreviewed; 580 AA.
AC I3JXD7;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Dynein cytoplasmic 1 intermediate chain 1 {ECO:0000313|Ensembl:ENSONIP00000013532.2};
GN Name=DYNC1I1 {ECO:0000313|Ensembl:ENSONIP00000013532.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000013532.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000013532.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the dynein intermediate chain family.
CC {ECO:0000256|ARBA:ARBA00011059}.
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DR AlphaFoldDB; I3JXD7; -.
DR Ensembl; ENSONIT00000013542.2; ENSONIP00000013532.2; ENSONIG00000010764.2.
DR eggNOG; KOG1587; Eukaryota.
DR GeneTree; ENSGT00940000156032; -.
DR TreeFam; TF300553; -.
DR Proteomes; UP000005207; Linkage group LG22.
DR GO; GO:0005868; C:cytoplasmic dynein complex; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR025956; DYNC1I1/DYNC1I2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR12442:SF34; CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 1; 1.
DR PANTHER; PTHR12442; DYNEIN INTERMEDIATE CHAIN; 1.
DR Pfam; PF11540; Dynein_IC2; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 445..492
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 68..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 142..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..37
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..91
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..164
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..184
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 580 AA; 65231 MW; B0A239A37E6367C8 CRC64;
MSDKSDLKAE LERKKQRLAQ IREEKKRKEE ERKKKEVRKK VSKFPPSSLI LYVFLFCVRL
TDFLSVPTPV SPSKSVSTPS ETGSQDSADG GAAGRTLQWD TDPSVLQLQA DSELGRRMQR
LGASKITQVD FLPKEVVSYS KETQTPTCTL SEEEEEEDEE LMETKPGPES EQQDEDDNRE
SKEGSFPVLR ELTEEERQQI LHSSEFQSFF DCSIRVMERA LAEDSEIFFD YSGRDLDDKE
GIYLQFHFYF HFTKPPTFSF LSQYPELLVA SYNNNEDAPH EPDGVALVWN IKFKKATPEY
IFHCQSPVVS VGFARFHPNL VVGGTYSGQI VLWDNRSHRR TPVQRTPLSA AAHTHPVYCV
NVVGTQNANN LITVSTDGRM CSWSLDMLSQ PQETMELVYN KSKPVAVTCM AFPTGDVNNY
VVGSEEGTVY TASRHGSKAG ICEMFEGHQG PVTGISCHSA VGTVDFSHLF ITSSFDWTVK
LWSTKHNKPL YSFEDNADYV YDVMWSPVHP AMFAAVDGMG RLDLWNLNND TEVPTASVTI
EGASALNRVR WSSGGKEVAV GDSEGRVWIY DTGEVLELTV
//
