ID I3KDE3_ORENI Unreviewed; 646 AA.
AC I3KDE3;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Mucosa-associated lymphoid tissue lymphoma translocation protein 1 {ECO:0000313|Ensembl:ENSONIP00000019138.2};
GN Name=LOC102077990 {ECO:0000313|Ensembl:ENSONIP00000019138.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000019138.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000019138.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005470805.1; XM_005470748.3.
DR RefSeq; XP_019217158.1; XM_019361613.1.
DR AlphaFoldDB; I3KDE3; -.
DR STRING; 8128.ENSONIP00000019138; -.
DR Ensembl; ENSONIT00000019155.2; ENSONIP00000019138.2; ENSONIG00000015206.2.
DR GeneID; 102077990; -.
DR KEGG; onl:102077990; -.
DR CTD; 571242; -.
DR eggNOG; ENOG502QUZM; Eukaryota.
DR GeneTree; ENSGT00390000018044; -.
DR HOGENOM; CLU_014796_0_0_1; -.
DR InParanoid; I3KDE3; -.
DR OMA; GYACEDA; -.
DR OrthoDB; 3080800at2759; -.
DR TreeFam; TF319744; -.
DR Proteomes; UP000005207; Linkage group LG7.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.3360; -; 1.
DR Gene3D; 3.40.50.1460; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR029030; Caspase-like_dom_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR041077; MALT1_Ig.
DR InterPro; IPR033540; MALT1_IG-like_dom_sf.
DR InterPro; IPR011600; Pept_C14_caspase.
DR InterPro; IPR001309; Pept_C14_p20.
DR PANTHER; PTHR22576; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE; 1.
DR PANTHER; PTHR22576:SF38; MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF18703; MALT1_Ig; 1.
DR Pfam; PF00656; Peptidase_C14; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF52129; Caspase-like; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50208; CASPASE_P20; 1.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 6..79
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 110..190
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 205..282
FT /note="Caspase family p20"
FT /evidence="ECO:0000259|PROSITE:PS50208"
SQ SEQUENCE 646 AA; 71986 MW; ABF0D0634CF3FF57 CRC64;
MTGSFPKHTM ISEIVIVRHP VSACVPVNHK VTLSVRAQGT GILNYQWFTD GRKEEPGGTQ
ADLTIKAQET QLYVCRVNDQ HYNCVFSNWV KVKVLDIDKS GLPIDWQGEP HIATNPKPQK
IKPGTKLTLH CAAFGIPAPS YQWYRNGQPL LDMTSGTLQI EHATAEHSGT YLCSLSNTLE
ERWTEAVDVD IVQSDQPPPA VLTATDKVAL LIGNLNYSNH PALMAPVMDV HELGNLLRQL
GFRVVSLLDL TREEMLTAIE KFIHLLDKGV YGLFYYAGHG YEHAGRNYLV SVDAPQPYGT
ENCVCVQRIM LSMQERQTAL SVILLDTCRK WYNQGSLLSA IKPLAPSGNT VYGYATCEDA
EAFEVQDGGK STGIFTKYLN KHILQAEKVT HVLEKVSEDL GRDPLITGKQ AVEIKHTLKE
PRSLADPVRT TGHTKELHLR DACWRQANEL PRKKRLMFLC GVEVEVSFSA LYSNVLVAFA
TVKTTGTHTQ DCVVTLSSIP TMEDIFSRSG RSEEMDSLLL MNNGNPDCTL RLCALQKLKE
SMVIKVDLHY THRDSKLRQT ESQRVDIGKP LVASCKLYRR NHGATGRTRE GNFAKSMGNI
ASSNPLLHQT GSCRPFTRKA VCAAKIPVTW SNEPEENDEN DFSCPH
//
