ID I3KDE4_ORENI Unreviewed; 528 AA.
AC I3KDE4;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Amine oxidase {ECO:0000256|RuleBase:RU362067};
DE EC=1.4.3.- {ECO:0000256|RuleBase:RU362067};
GN Name=LOC100703044 {ECO:0000313|Ensembl:ENSONIP00000019139.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000019139.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000019139.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|RuleBase:RU362067};
CC -!- SIMILARITY: Belongs to the flavin monoamine oxidase family.
CC {ECO:0000256|RuleBase:RU362067}.
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DR RefSeq; XP_005465554.1; XM_005465497.3.
DR AlphaFoldDB; I3KDE4; -.
DR STRING; 8128.ENSONIP00000019139; -.
DR Ensembl; ENSONIT00000019156.2; ENSONIP00000019139.1; ENSONIG00000015207.2.
DR GeneID; 100703044; -.
DR KEGG; onl:100703044; -.
DR eggNOG; KOG0029; Eukaryota.
DR GeneTree; ENSGT00940000160928; -.
DR HOGENOM; CLU_004498_8_3_1; -.
DR InParanoid; I3KDE4; -.
DR OrthoDB; 3597164at2759; -.
DR TreeFam; TF313314; -.
DR Proteomes; UP000005207; Linkage group LG3.
DR GO; GO:0008131; F:primary amine oxidase activity; IEA:UniProt.
DR Gene3D; 1.10.10.1620; -; 1.
DR Gene3D; 3.30.70.2100; -; 1.
DR Gene3D; 3.50.50.100; -; 1.
DR Gene3D; 3.90.660.10; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.10.405.10; Guanine Nucleotide Dissociation Inhibitor, domain 1; 1.
DR InterPro; IPR002937; Amino_oxidase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR001613; Flavin_amine_oxidase.
DR PANTHER; PTHR10742; FLAVIN MONOAMINE OXIDASE; 1.
DR PANTHER; PTHR10742:SF21; L-AMINO-ACID OXIDASE; 1.
DR Pfam; PF01593; Amino_oxidase; 1.
DR PRINTS; PR00757; AMINEOXDASEF.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU362067};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU362067};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU362067};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..528
FT /note="Amine oxidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003674533"
FT DOMAIN 72..511
FT /note="Amine oxidase"
FT /evidence="ECO:0000259|Pfam:PF01593"
SQ SEQUENCE 528 AA; 59699 MW; 635E6210A82CA076 CRC64;
MKPQFAKWKF FHSVAISVLL LALYPTAAVA SMNEELAKCL EDDDNYRLMD TVKTGLPQIK
KSHHVIIVGA GIAGLTAAKL LEGAGHKVTI IEASPRVGGR VETYRDEENG WYADLGAMRI
PNNHKIVRWY IKEMGLKLNP FIMYDSNTFY LVNERNRTRT YAVTANPDIL NYTLPERERG
KSADQLLWQA LQKVRDEINA HGCKAAFKKY DHYSVKEYLK EEGGLSPEAV VMIAELLNEQ
SMMHLALTEM LYVENDVSDN TTYDEITGGT DLLPKAFLSF IDAPILFNSK VKFISQSKEG
VTVSYRRKGE SALTYITGDA VLVTTTAKAA LFLDFKPPLS IQKMEALRAV HYESSTKIIL
TFKRKFWVDD GIQGGKSITD RPSRYIYYPS HSFPRNQTIG VLLASYTWAD DAQFLQGATD
EDLKELALKD LAKIHGEQVW DLCIGVVVKR WGIDPYSLGG FAFFTPYQHI EYAKELFRSE
GRVHFAGEHT AFPHAWIETS MKSAIRAAKN INNAAHEESA RNQHRNEF
//
