ID I3KU92_ORENI Unreviewed; 748 AA.
AC I3KU92;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Golgin subfamily A member 5 {ECO:0000256|ARBA:ARBA00020370};
DE AltName: Full=Golgin-84 {ECO:0000256|ARBA:ARBA00032404};
GN Name=golga5 {ECO:0000313|Ensembl:ENSONIP00000024688.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000024688.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000024688.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Involved in maintaining Golgi structure. Stimulates the
CC formation of Golgi stacks and ribbons. Involved in intra-Golgi
CC retrograde transport. {ECO:0000256|ARBA:ARBA00024833}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004409}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004409}.
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DR RefSeq; XP_003445518.1; XM_003445470.4.
DR AlphaFoldDB; I3KU92; -.
DR Ensembl; ENSONIT00000024709.2; ENSONIP00000024688.2; ENSONIG00000019609.2.
DR GeneID; 100699293; -.
DR KEGG; onl:100699293; -.
DR CTD; 9950; -.
DR GeneTree; ENSGT00390000018470; -.
DR HOGENOM; CLU_022484_0_0_1; -.
DR InParanoid; I3KU92; -.
DR OMA; CSSYEAH; -.
DR OrthoDB; 3152258at2759; -.
DR Proteomes; UP000005207; Linkage group LG19.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007030; P:Golgi organization; IEA:InterPro.
DR InterPro; IPR019177; Golgin_subfamily_A_member_5.
DR PANTHER; PTHR13815:SF7; GOLGIN SUBFAMILY A MEMBER 5; 1.
DR PANTHER; PTHR13815; GOLGIN-84; 1.
DR Pfam; PF09787; Golgin_A5; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 717..738
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 49..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 95..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 246..463
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 490..646
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 95..122
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..202
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 748 AA; 83555 MW; 11DB5C32CDCEBFFC CRC64;
MSWFTDLAGK AEDFLNKVDQ GAATALSKGQ EKSSSFSIAY GEESTAKTDY NSAGYKTNPP
VTHHTYASSH DAQSYISSAA GNIKKSNATV LAGSANVTST PLGSGSSAPN TSKTSSGFVR
PKKSEQNVDD DMLFDFLNSS EPQVSNRRDS RKELVKVVEA QNPTSPASTT SYTTPSVPST
PPSTRGVSRA SSMSSLSAHS IKTEENSAKE QGQDTPESSD SGLAVPQESN RQEPPPPTEE
PQNQILSSLR LENQLLRSEV ASLNQEMASV IQRAKDLQDE LNQARLRADK WNSEQSQTDR
TLRELRSQVD DLTEALSAKD GQLAVLKIRL DEADQLLKSR SAALEEAQKE KSKIMQDHTE
GNSMQSQALE TLQERLREAE LALRREQDNY RQMQTEYAGR LSKLEAERQT LAETVTAAER
RAAEEKFKID DFQHQLKSAK AAAESAKQEL QDYKQKASRI LQSKEKLISS LKEGSGLDAL
DGSGTMALEL EELRHEKDLQ REEIQKLQGQ VLTLRTEIQD LENQALAEAE TWREQQAQLQ
EQQALQNRAK QEVEAEVERY KQELQYLEEE HHRAKTTLQS RIKDREDEIQ KLRNQLTNKT
LSSSQTELEN RLHQLTETLI QKQTMLEALG TEKNSLVFQL ERLEQQLKNT QGGQSGGPAI
NMSGLEGAGA RQRNTPVLFS DQDSPGVYGK VRKAASTIDR FSIRLGIFLR RYPMARVFVI
LYMAVLHLWV MIVLLTYTPE MHGRPDGR
//
