ID I3KVE3_ORENI Unreviewed; 1061 AA.
AC I3KVE3;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Tudor domain containing 7 {ECO:0000313|Ensembl:ENSONIP00000025089.2};
GN Name=tdrd7 {ECO:0000313|Ensembl:ENSONIP00000025089.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000025089.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000025089.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR AlphaFoldDB; I3KVE3; -.
DR Ensembl; ENSONIT00000025110.2; ENSONIP00000025089.2; ENSONIG00000019919.2.
DR GeneTree; ENSGT00890000139482; -.
DR HOGENOM; CLU_283554_0_0_1; -.
DR Proteomes; UP000005207; Linkage group LG3.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR CDD; cd09974; LOTUS_3_TDRD7; 1.
DR CDD; cd20428; Tudor_TDRD7_rpt2; 1.
DR Gene3D; 2.30.30.140; -; 3.
DR Gene3D; 2.40.50.90; -; 3.
DR Gene3D; 3.30.420.610; LOTUS domain-like; 3.
DR InterPro; IPR041966; LOTUS-like.
DR InterPro; IPR025605; OST-HTH/LOTUS_dom.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR037978; TDRD7_LOTUS_3.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR047448; Tudor_TDRD7_rpt2.
DR PANTHER; PTHR22948; TUDOR DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22948:SF29; TUDOR DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF12872; OST-HTH; 2.
DR Pfam; PF00567; TUDOR; 3.
DR SMART; SM00333; TUDOR; 3.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 3.
DR PROSITE; PS51644; HTH_OST; 3.
DR PROSITE; PS50304; TUDOR; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 3..76
FT /note="HTH OST-type"
FT /evidence="ECO:0000259|PROSITE:PS51644"
FT DOMAIN 198..268
FT /note="HTH OST-type"
FT /evidence="ECO:0000259|PROSITE:PS51644"
FT DOMAIN 286..356
FT /note="HTH OST-type"
FT /evidence="ECO:0000259|PROSITE:PS51644"
FT DOMAIN 455..513
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 82..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 268..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 355..379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 797..868
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..153
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 797..821
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 838..859
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1061 AA; 118339 MW; 1655FC402289C65E CRC64;
MADAEVAKKM LRGILQSNKG GVSLSHLQSE YKELTGEHIP HKQMGHSNLD ALLANMPSLV
RMERSRSGEV CVDDITKVVA RQRTSKKTGR PHLVNTQMRV KPAAPLVLNA KPQNSLRQPN
HRGRGGGRGG GPGRGHPNKM SSQNTSNRKG NQPPDKRMTL PSRFQKEVHA HLSRNSQQTA
PPSNLNESFG SGKGKPYNPQ LVQGHIREIL AKYSNGFWVS KLPQMYRELY KQDLPTEAIK
DLETWTHICI VEKTCSSNPS ERLLYPAKEQ TNTSSSSSPP SSPATLSPDL KQKLEELLVK
YSSGLWAHAL PKLFQDTYKT KLPGHVLVNL DLLSDICTID YPMPDNPKRA ILYRRSSTGG
GGGEDENCNR RNSSANEEEL RVRKELGRRL SNQAVPPLQI PKEEYPSVLV VEATNTNGVL
LRYIGEGYSQ AQESMEDEMR EFYGLDQSSP TPVSSLSSGQ LVAVRAEEEE EILRAQVCEV
MTDKVKVYYV DHGFSEVISK NKAFELHEKF FKLPFQATKC KLAGLEPFCQ DPAVLKKFET
MASGKILLAE ILERGQTPLV VLYDTSQDDD ININAACMKA LHDKSLASPL QVNSAYMNVT
ISSVCSDGTI YCQLPSRGLA KMNETLEKIE TYFHSQVTSE FLVSRPFCGK RCLARYKGKW
SRVEITNLHG SRVLDILFID VGVQASVEVF ELREIPPPFL RDLMAIPPQA VKCCLADLAV
SVGSWTPDAV QWLRDKVLNT TDCSMKVAKV DEKKRCIHVH LFTDKNFHDP DRSLNRQMAQ
SELLKQQPDV FLTSHRISTP TSSTKTSSAS NSTNGSPTSA NVPVKPHLRR ALSGPKGSGG
GGNTTTTPSS PTETPSSPTS SLQLPPPLEL PTIGNNMDVY VSLACHPGHF VLQPWGDMYR
LVVLMGEMIL YYNKTEEKPL NIEKNQIYAA KVENSWHRVL VKGVLNSGLV SVYELDYGKH
ELVSCTQLRP LIKEFRQLPF QGITAQLAGV KQRQWSEEAS IVFRHHVEKK PMVAQLEAVQ
EATNPWERKL TVFLVDTSQE EKDTWVHDIM AEFADELTNE L
//
