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Database: UniProt
Entry: I3LPL6_PIG
LinkDB: I3LPL6_PIG
Original site: I3LPL6_PIG 
ID   I3LPL6_PIG              Unreviewed;      1748 AA.
AC   I3LPL6;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 2.
DT   22-NOV-2017, entry version 39.
DE   SubName: Full=Sodium voltage-gated channel alpha subunit 11 {ECO:0000313|Ensembl:ENSSSCP00000026043};
GN   Name=SCN11A {ECO:0000313|Ensembl:ENSSSCP00000026043};
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;
OC   Sus.
OX   NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000026043, ECO:0000313|Proteomes:UP000008227};
RN   [1] {ECO:0000313|Ensembl:ENSSSCP00000026043, ECO:0000313|Proteomes:UP000008227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000026043};
RG   Porcine genome sequencing project;
RL   Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSSCP00000026043}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2012) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSSSCP00000026043}.
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DR   EMBL; AEMK02000085; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PRIDE; I3LPL6; -.
DR   Ensembl; ENSSSCT00000023912; ENSSSCP00000026043; ENSSSCG00000029419.
DR   GeneTree; ENSGT00830000128242; -.
DR   Proteomes; UP000008227; Chromosome 13.
DR   ExpressionAtlas; I3LPL6; differential.
DR   GO; GO:0044299; C:C-fiber; IEA:Ensembl.
DR   GO; GO:0070062; C:extracellular exosome; IEA:Ensembl.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:Ensembl.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR028821; Na_channel_a11su.
DR   PANTHER; PTHR10037:SF210; PTHR10037:SF210; 3.
DR   Pfam; PF00520; Ion_trans; 3.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008227};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   1748 AA;  200564 MW;  23CA5875EC4F8D69 CRC64;
     MDDRCYPVIF PDARNFCPFT PDSLAAIEKQ IAIQKEKKNS KDQTAPEPQH RPQLDLKVSR
     KLPKLYGDIP PELIAKPLED LDPFYRNHKT FMVLNKNRTI YRFSAKRALF IFGPFNSIRS
     LAIRISTRVT LFSMFIICTV VINCVFMATA HGKKSIFVLH ASVLSLIKIL ARGFILDEFS
     FLRDPWNWLD SIVIATVSSI SLSSLRTFRV FRALKAISVV SGLKVIVGAL LRSVKKLVDV
     MILTLFCLSI FALVGQQLFM GSLDQKCVSK DCDSDNKVCN SPSFPLFPIS RACSEQFECN
     HTRWNPDYNY TNFDNFGWSF LAMFRLMTQD SWEKLYRQTL RTSGLYSVFF FVLVIFLGSF
     YLINLTLAVV TMAYEEQNKN VAAETEAKEK MFQEAQQLLK EEKEALVAMG IDRSSLNSLE
     ASSFSPKKRR LFGNKKRKSF FLRESGKDQV PGSDSDEDSS KKPHLLEQTK RLSQNLSVDY
     SDEHGDPLQR QRALSAVSIL TITMHEQEKS QEPCLPCGEN LASKYLVWDC NPQWLCIKKA
     LRLVMTDPFT ELAITICIII NTIFLAMEHY QMDTSFETML CTGNLVFAGI FMAEMCLKII
     ALDPYHYFRR GWNIFDSIVA LLSFADVMLN TEKKSWKLFR SLRVLRVFKL AKSWPTLNTL
     IKIIGHSVGA LGNLTVVLAI VVFIFSVVGM QLFGSRFNST RTNSKSRDCA NSCLRRWHME
     DFYHSFLVVF RILCGEWIEN MWECMQEANQ PLCIIVFLSI MVIGKLVVLN LFIALLLNSF
     SNEERDGQLE GEGRKTKVHL ALDRFRRAFC FVLYTLEHFW RKWRKKQHLP KQKEMTERPA
     TEGKDVIPLV TKIKKGPETW EEFCALSSAP RTSSVGNDWT WLAPLAEEED DVESLCEHMA
     HPVRQPEAGQ QACELHHKNK ESNSPGVQSV EIDIFSEDVP YLSIQNSRKK SDAATSVLSE
     CSTIDPQDPF RHIPEMVPKK EPERCLPRGL GCCFPCCALD KRKSPWIIWW KLRKTCYQIV
     NHSWFESFII FVILLSSGAL VFEDIHLEKQ PQIQTLLNCT DHIFTYIFVL EMGLKWVAFG
     FQKYFTSAWC WLDFVIVIVS VTSLIDVKGL KSFRTLRALR PLRALSQFEG MKVVVYALIG
     AIPAILNVLL VCLIFWLIFC ILGVHFFSGK FGRCVNVTDE NAVINDSLVT NRNQCESENL
     SWMPQSVNFD NVGMAYLALL QVATFKGWMD IMYAAVDSRE EGKQPRFEEN PYVYLYFVVF
     IIFGSFFTLN LFIGVIIDNF NQQQKKISGQ DIFMTEEQKK YYNAMKKLGS KKPQRPIPRP
     LNKCQGLVFD LVTHQVFDII IIILIFLNMV SMMAESHDQS DRMKLILERL NLAFVVIFTM
     ECLIKIFALR QYYFTNGWNL FDCVIVILSI VSTMVSVLED QEHIPFPPTL FRVVRLARIG
     RILRLVRAAR GIRTLLFALM MSLPSLFNIG LLLFLIMFIY AIFGMNSFCK VKQGSGIDDI
     FNFETFVGSM LCLFQITTSA GWDALLNPML QSKDSCNRTS ENCHLSAIAT TYFVSYIIIS
     FLIVVNMYIA VILENFNTAT EESEDPLGED DFEMFYEVWE KFDPEATQFI KYSALSDFAD
     ALPEPLRVAK PNKYQFLVMD LPMVSGDRLH CLDILFAFTA RVLGESSGLD SIKAMMEEKF
     MEANPFKKLY EPIKEEERCA AVIQKAFRKY MTKMTKCTLE DRPHSPLQTL CNGDLSNSGM
     AEGKVHYD
//
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