ID I3LSW6_PIG Unreviewed; 241 AA.
AC I3LSW6;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Aminoacyl tRNA synthetase complex interacting multifunctional protein 2 {ECO:0000313|Ensembl:ENSSSCP00000027209.3};
GN Name=AIMP2 {ECO:0000313|Ensembl:ENSSSCP00000027209.3,
GN ECO:0000313|VGNC:VGNC:85203};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000027209.3, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000027209.3, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000027209.3,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000027209.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; I3LSW6; -.
DR Ensembl; ENSSSCT00000030527.4; ENSSSCP00000027209.3; ENSSSCG00000024245.4.
DR VGNC; VGNC:85203; AIMP2.
DR GeneTree; ENSGT00390000015826; -.
DR TreeFam; TF352214; -.
DR Proteomes; UP000008227; Chromosome 3.
DR Bgee; ENSSSCG00000024245; Expressed in oocyte and 43 other cell types or tissues.
DR ExpressionAtlas; I3LSW6; baseline and differential.
DR GO; GO:0017101; C:aminoacyl-tRNA synthetase multienzyme complex; IEA:InterPro.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.1050.130; -; 1.
DR InterPro; IPR042360; AIMP2.
DR InterPro; IPR041503; AIMP2_thioredoxin.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR004046; GST_C.
DR PANTHER; PTHR13438; AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN; 1.
DR PANTHER; PTHR13438:SF2; AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 2; 1.
DR Pfam; PF00043; GST_C; 1.
DR Pfam; PF18569; Thioredoxin_16; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
PE 1: Evidence at protein level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteomics identification {ECO:0007829|PeptideAtlas:I3LSW6};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 40..129
FT /note="AIMP2 thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18569"
FT DOMAIN 165..223
FT /note="Glutathione S-transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00043"
SQ SEQUENCE 241 AA; 26481 MW; 34C68EFAA8654008 CRC64;
MIQTPDADLD VTNIIQAEEP AALATSAFDL NSVLGKDYGA LKDIVINANP ASPPLSLLVL
HRLLCDHYRV LSAVHTHSAV QRVPPHLLKC FGEQKQQPRH EYQLGFTLIW KDVPKTQMKF
SVQTMCPIEG EGNIARFLFS LFGRKQDAVS LTLMDSWVDT AVFQLKEGSS KEKAAVFRSM
NSALGKSPWL VGNELTVADV VLWSALRQTG ACGAVVPASV QKWMGACENL APFHTALQLL
R
//
