ID I3M2K9_ICTTR Unreviewed; 461 AA.
AC I3M2K9;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Fibrinogen C domain containing 1 {ECO:0000313|Ensembl:ENSSTOP00000003227.3};
GN Name=FIBCD1 {ECO:0000313|Ensembl:ENSSTOP00000003227.3};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000003227.3, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000003227.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Homotetramer; disulfide-linked.
CC {ECO:0000256|ARBA:ARBA00038769}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
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DR EMBL; AGTP01020232; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01020233; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01020234; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01020235; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005321239.1; XM_005321182.1.
DR AlphaFoldDB; I3M2K9; -.
DR STRING; 43179.ENSSTOP00000003227; -.
DR Ensembl; ENSSTOT00000003602.3; ENSSTOP00000003227.3; ENSSTOG00000003601.3.
DR GeneID; 101965701; -.
DR CTD; 84929; -.
DR eggNOG; KOG2579; Eukaryota.
DR GeneTree; ENSGT00940000155976; -.
DR HOGENOM; CLU_038628_5_0_1; -.
DR InParanoid; I3M2K9; -.
DR OrthoDB; 3134470at2759; -.
DR TreeFam; TF351983; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008061; F:chitin binding; IEA:UniProtKB-KW.
DR CDD; cd00087; FReD; 1.
DR Gene3D; 3.90.215.10; Gamma Fibrinogen, chain A, domain 1; 1.
DR InterPro; IPR036056; Fibrinogen-like_C.
DR InterPro; IPR014716; Fibrinogen_a/b/g_C_1.
DR InterPro; IPR002181; Fibrinogen_a/b/g_C_dom.
DR InterPro; IPR020837; Fibrinogen_CS.
DR NCBIfam; NF040941; GGGWT_bact; 1.
DR PANTHER; PTHR19143:SF45; FIBRINOGEN C DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR19143; FIBRINOGEN/TENASCIN/ANGIOPOEITIN; 1.
DR Pfam; PF00147; Fibrinogen_C; 1.
DR SMART; SM00186; FBG; 1.
DR SUPFAM; SSF56496; Fibrinogen C-terminal domain-like; 1.
DR PROSITE; PS00514; FIBRINOGEN_C_1; 1.
DR PROSITE; PS51406; FIBRINOGEN_C_2; 1.
PE 4: Predicted;
KW Chitin-binding {ECO:0000256|ARBA:ARBA00022669};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 235..458
FT /note="Fibrinogen C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51406"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 216..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 461 AA; 50858 MW; 1AF43C5DB0DA09BC CRC64;
MVNDRWKTMG GASQLEERPR DKPQRPSCGY VLCTVLLSLA VLLAVAVTSA VLFLNHVHVP
GTAPPPIVST GPAGANSALV TVERADSSRL SILIDPRCPD LADGFARLEG AQASVLRALT
EHQAQPQLAD TQEQELLDTL ADQLPRLLAR ASELQAECTG LRKGHSMLGQ GLSTLQHEQG
RLIQLLSESQ GHLAHLVNSV GDVLDALQRD RGLSRPRVKA DLQRAPSRGA RPRGCANGSR
PRDCLDVLLS GQQDDGVYSV FPTHYPAGFQ VYCDMRTDGG GWTVFQRRED GSVNFFRGWE
AYREGFGQLT GEHWLGLKRI HALTTQAVYE LHVDLEDFDN GTAYARYGSF GVGLFSVDPE
EDGYPLTVAD YSGTAGDSLL KHSGMRFTTK DRDSDHSENN CAAFYRGAWW YRNCHTSNLN
GQYLRGAHAS YADGVEWSSW TGWQYSLKFS EMKIRPVRED H
//
