ID I3M4K5_ICTTR Unreviewed; 705 AA.
AC I3M4K5;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=IQ motif containing E {ECO:0000313|Ensembl:ENSSTOP00000004143.3};
GN Name=Iqce {ECO:0000313|Ensembl:ENSSTOP00000004143.3};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000004143.3, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000004143.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01110614; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01110615; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01110616; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01110617; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3M4K5; -.
DR STRING; 43179.ENSSTOP00000004143; -.
DR Ensembl; ENSSTOT00000004617.3; ENSSTOP00000004143.3; ENSSTOG00000004604.3.
DR GeneTree; ENSGT00940000163679; -.
DR HOGENOM; CLU_015416_1_0_1; -.
DR InParanoid; I3M4K5; -.
DR TreeFam; TF351136; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0060170; C:ciliary membrane; IEA:Ensembl.
DR GO; GO:0009898; C:cytoplasmic side of plasma membrane; IEA:Ensembl.
DR GO; GO:0098797; C:plasma membrane protein complex; IEA:Ensembl.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0120229; P:protein localization to motile cilium; IEA:Ensembl.
DR GO; GO:0008589; P:regulation of smoothened signaling pathway; IEA:Ensembl.
DR Gene3D; 1.20.5.190; -; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR PANTHER; PTHR22590:SF3; IQ DOMAIN-CONTAINING PROTEIN E; 1.
DR PANTHER; PTHR22590; UNCHARACTERIZED; 1.
DR Pfam; PF00612; IQ; 2.
DR SMART; SM00015; IQ; 3.
DR PROSITE; PS50096; IQ; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 54..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 330..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 435..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 600..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 137..219
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 357..373
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..454
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 570..586
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 705 AA; 77955 MW; FA3A5B36CF4DB24D CRC64;
MAAGGLAGRG PGSRCRVLRR PGSAAAMSQG LVEAASETGD DSLSAITFDS DFETKARRKG
FHKPPTSPKS PYYSKPRKAA SWRSLRTVGS MPLSGRMSLT PQKLWLGAPK QGHVPGTTVY
REKEDMYDEI IELKKSLHTK KSDVDLMRTK LRRLEEENNR KDRQIEQLLD PGRGPDFVRT
LAEKRPDAGW VINGLKQRIF KLEQQCKEKD STINKLQTDM KTTNLEEMRI AMDTYYEEIH
RLQTLLASSD VAGKKLPMDK KVGMKRQKKM SSTLLNLSRS VQELTEENQS LKEDLDRVLS
NSPTISRLKG YVDWSKPRLL RRIAELEKKV SSMENAKPHS SESHRPTPLA HSISNSAAHK
HPRDRPEEQE RLRGAVKSLK AERSALQAQL QEKDVEVKQL LQAKADLEKE LESMREGKQD
RQEHEQVLRE EIQTLTNKCQ EPEEAKKEEP SAPMEVTREA CGELCTPPPS NRHSQQDSEV
DSGPEGCPQP LSPIPCSDGR KESAARTLQA SWKAHRHKKK KKAVLNEAAT LLQAVFRGHL
SRTKLLLSKS CGSESPGLLG VPEQSSPTPC VPSPSAQAES NPGQEEAIAT IQSVLRGHLA
RAKLTSSGGK RTATTVPSRA APAMHPETSP PSWTASPGEK SQLSGEEVAE DEPEEPAGAQ
PHAAGFSSVE LQPVKPPALD DINSDDSDDV VFMPPLPTKK TPSPF
//
