ID I3M8J9_ICTTR Unreviewed; 1074 AA.
AC I3M8J9;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=RIMS binding protein 2 {ECO:0000313|Ensembl:ENSSTOP00000006075.3};
GN Name=RIMBP2 {ECO:0000313|Ensembl:ENSSTOP00000006075.3};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000006075.3, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000006075.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RIMBP family.
CC {ECO:0000256|ARBA:ARBA00010749}.
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DR EMBL; AGTP01088711; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01088712; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3M8J9; -.
DR STRING; 43179.ENSSTOP00000006075; -.
DR Ensembl; ENSSTOT00000006794.3; ENSSTOP00000006075.3; ENSSTOG00000006781.3.
DR eggNOG; KOG3632; Eukaryota.
DR GeneTree; ENSGT00950000183203; -.
DR HOGENOM; CLU_001979_0_0_1; -.
DR InParanoid; I3M8J9; -.
DR TreeFam; TF316230; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR CDD; cd00063; FN3; 3.
DR CDD; cd12014; SH3_RIM-BP_1; 1.
DR CDD; cd12012; SH3_RIM-BP_2; 1.
DR CDD; cd12013; SH3_RIM-BP_3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR035753; RIM-BP_SH3_2.
DR InterPro; IPR035755; RIM-BP_SH3_3.
DR InterPro; IPR040325; RIMBP1/2/3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14234; RIM BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR14234:SF18; RIMS-BINDING PROTEIN 2; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF14604; SH3_9; 2.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00326; SH3; 3.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50002; SH3; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 160..227
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 482..583
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 847..915
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 951..1018
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 582..662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 690..847
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1025..1055
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1..57
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 582..601
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 702..719
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1074 AA; 117710 MW; 8A25FBB90CF0E487 CRC64;
MREAAERRQQ LELEHEQALA VLNAKQQEIE LLQKCKVREL EEKCRTQSEQ FSRLSRDLEK
FRQQAGKIDL LGSGSVASLD IPLAPSKPFP QFMNGLATSI GKGHESAPGH YPAVGDYSPL
SGGKPELLST NPTFLSPPSC RHRGMDNEQN SNTSKQRYSG KVHLCVARYS YNPFDGPNEN
PEAELPLTAG KYLYVYGDMD EDGFYEGELL DGQRGLVPSN FVDFIQDNES RLASTLGTEQ
DQNFINHSGL GLGSENILDL HSPTRTDPGI TDDGGGTLDV NIDDIGEDIV PYPRKITLIK
QLAKSVIVGW EPPAVPPGWG TVSSYNVLVD KETRVSLALG SRTKALIEKL NTAACTYRIS
VQCVTSRGSS DELRCTLLVG KDVAVAPSHL RVDNITQISA RLSWLPTNSN YSHVIFLNEE
EFDVVKAARY KYQFLNLRPN MAYKVKVLAK PHQMPWQLPL EQREKKEAFV EFSTLPAGPP
APPQDVTVQA GAMASTIQVS WKPPMLTPTG LSNGANVTGY GVYAKGQRVA EVIFPTADST
AVELVRLRSL EAKAVTVRTL SAQGESVDSV FAAIPLDLLV PPTPHPRAAP PPKPLPSAPD
TKDKPLCPHT KVEEPWEQSR TPAPVHGHML EPPDLQGSGP GRRSPSPSRI LPQPQGAPVS
TTVAKAMARE AAQRVAESSR LEKRSLLPER SSLGRCASSD EEDGFASPEL KRRGASVDDF
LKGSELGKPP PCCHGDEYPT ESSRGSDLSD IMEEDEEELS SEMQLEDGGR RRPSGTSHNA
LKILGNPASA GRVDRADHVG RRFSHGGTGP QRPRPTVVPS IDDYAGRDRL SPDFYEESET
DPGAEEPPAR IFVALFDYDP LTMSPNPDAA EEELPFKEGQ IIKVYGDKDA DGFYRGETCA
RLGLIPCNMV SEIQADDEEM TDQLLRQGFL PLSTPVEKIE RSRRSSRQRP VSTRRVVALY
DYDPRESSPN VDVEAELTFC TGDIITVFGE IDEDGFYYGE LNGLKGLVPS NFLEEVPEDV
EVYLSDAPSP YSQDPPPRSK AKRVSTPPPA SWAPPLPCVD DHSCFCILGQ KHTP
//
