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Database: UniProt
Entry: I3MCU2_ICTTR
LinkDB: I3MCU2_ICTTR
Original site: I3MCU2_ICTTR 
ID   I3MCU2_ICTTR            Unreviewed;      1833 AA.
AC   I3MCU2;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 2.
DT   22-NOV-2017, entry version 38.
DE   SubName: Full=Sodium voltage-gated channel alpha subunit 4 {ECO:0000313|Ensembl:ENSSTOP00000008103};
GN   Name=SCN4A {ECO:0000313|Ensembl:ENSSTOP00000008103};
OS   Ictidomys tridecemlineatus (Thirteen-lined ground squirrel)
OS   (Spermophilus tridecemlineatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha;
OC   Sciuridae; Xerinae; Marmotini; Ictidomys.
OX   NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000008103, ECO:0000313|Proteomes:UP000005215};
RN   [1] {ECO:0000313|Ensembl:ENSSTOP00000008103}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Assembly & Analysis Group;
RG   Computational R&D Group;
RG   and Sequencing Platform;
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT   "The Draft Genome of Spermophilus tridecemlineatus.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSTOP00000008103}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2012) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSSTOP00000008103}.
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DR   EMBL; AGTP01052575; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGTP01052576; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 43179.ENSSTOP00000008103; -.
DR   Ensembl; ENSSTOT00000009041; ENSSTOP00000008103; ENSSTOG00000009013.
DR   eggNOG; ENOG410KCTY; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00830000128242; -.
DR   InParanoid; I3MCU2; -.
DR   OMA; NDEANYY; -.
DR   OrthoDB; EOG091G00FK; -.
DR   TreeFam; TF323985; -.
DR   Proteomes; UP000005215; Unassembled WGS sequence.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR008052; Na_channel_a4su_mammal.
DR   InterPro; IPR010526; Na_trans_assoc.
DR   Pfam; PF00520; Ion_trans; 3.
DR   Pfam; PF06512; Na_trans_assoc; 1.
DR   PRINTS; PR01665; NACHANNEL4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005215};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   1833 AA;  207610 MW;  C9CE43C0E39C5770 CRC64;
     MASSSLPTLV PIGPDCLRPF TRESLAAIER RAAEEEARLQ RNKQMEIEEP ERKPRSDLEA
     GKNLPLIYGD PPPEVIGIPL EDLDPYYSDK KTFIVLNKGK AIFRFSATPA LYMLSPFSIV
     RRGAIKVMFI MITILTNCVF MTMSDPPSWS KDVEYTFTGI YTFESLIKML ARGFCIDDFT
     FLRDPWNWLD FSVITMAYVT EFVDLGNISA LRTFRVLRAL KTITVIPGLK TIVGALIQSV
     KKLSDVMILT VFCLSVFALV GLQLFMGNLR QKCVRWPPPF NDTNTTWYGN DTWYANDTWY
     ANDTWNTNDT WNFHDSWASN YTFDWDAYIN DEANYYFLKD ANDALLCGNS SDAGHCPQGY
     ECIKAGRNPN YGYTSYDTFS WAFLALFRLM TQDYWENLFQ LTLRAAGKTY MIFFVVIIFL
     GSFYLINLIL AVVAMAYAEQ NEATLAEDQE KEEEFQQMLE KLKKHQEELE KAKATQALEG
     VEADGDPAHS QACNGSLDTS PGEKGPPRPS CSADSGISDA MEELEEAHQK CPPWWYKCAH
     KVLIWNCCTP WVKFKHIIHV IVMDPFVDLG ITICIVLNTL FMAMEHYPMT EHFDNVLSVG
     NLVFTGIFTA EMVLKLIAMD PYEYFQQGWN IFDSFIVTLS LVELGLANVQ GLSVLRSFRL
     LRVFKLAKSW PTLNMLIKII GNSVGALGNL TLVLAIIVFI FAVVGMQLFG KSYKECVCKI
     AADCSLPRWH MHDFFHSFLI VFRILCGEWI ETMWDCMEVA GQPMCLTVFL MVMVIGNLVV
     LNLFLALLLS SFSADSLAAS DEDGEMNNLQ IAIARIKWGI SFAKTFLLGL LHGKILSPKE
     IILSIGELGG AEQAGEAGEG APGDEKKEPP PEEGDKDLKK DNHILNHMGL ADGPPSSIEL
     DHLNFINNPY LTIQVPIASE ESDLEMPTEE ETDTFSEPED VKKPPQPLYD GNSSVCSTAD
     YKPPEEDPAE QAEEDPDGEQ PEECFTEACV QRCPCLYVDI SQGRGKMWWT LRRACFKIVE
     HNWFETFIVF MILLSSGALA FEDIYIEQRR VIRTILEYAD KVFTYIFILE MLLKWVAYGF
     KVYFTNAWCW LDFLIVDVSI ISLVANWLGY SELGPIKSLR TLRALRPLRA LSRFEGMRVV
     VNALLGAIPS IMNVLLVCLI FWLIFSIMGV NLFAGKFYYC INTTTSERFD ISEVNNKSEC
     ESLMHTGQVR WLNVKVNYDN VGLGYLSLLQ VATFKGWMDI MYAAVDSREK EEQPQYEVNL
     YMYLYFVIFI IFGSFFTLNL FIGVIIDNFN QQKKKMRKDI FMTEEQKKYY NAMKKLGSKK
     PQKPIPRPQN KIQGMVYDFV TKQVFDITIM ILICLNMVTM MVETDDQSQL KVDILYNINM
     VFIIIFTGEC VLKMFALRQY YFTVGWNIFD FVVVILSIVG LALSDLIQKY FVSPTLFRVI
     RLARIGRVLR LIRGAKGIRT LLFALMMSLP ALFNIGLLLF LVMFIYSIFG MSNFAYVKKE
     SGIDDMFNFE TFGNSIICLF EITTSAGWDG LLNPILNSGP PDCDPTLENP GTSVRGDCGN
     PSIGICFFCS YIIISFLIVV NMYIAIILEN FNVATEESSE PLGEDDFEMF YETWEKFDPD
     ATQFIDYSRL SDFVDTLQEP LRIAKPNKIK LITLDLPMVP GDKIHCLDIL FALTKEVLGD
     SGEMDALKQT MEEKFMAANP SKVSYEPITT TLKRKHEEVC AIKIQRAYRR HLLQRSVKQA
     SYMYRHSQDG SGDGAPEKEG LIASTMSKMY GPENGDRAAQ SQGEETGPTT TGLTPVSPSD
     TTPPTPVSPS DAALPSSPPP GQTVRPGVKE SLV
//
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