ID I3MJC7_ICTTR Unreviewed; 244 AA.
AC I3MJC7;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=glutathione transferase {ECO:0000256|ARBA:ARBA00012452};
DE EC=2.5.1.18 {ECO:0000256|ARBA:ARBA00012452};
GN Name=LOC101964314 {ECO:0000313|Ensembl:ENSSTOP00000011238.2};
GN Synonyms=LOC101964591 {ECO:0000313|Ensembl:ENSSTOP00000030832.1};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000011238.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000011238.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the GST superfamily. Theta family.
CC {ECO:0000256|ARBA:ARBA00009899}.
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DR EMBL; AGTP01078036; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01078038; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01078039; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 43179.ENSSTOP00000011238; -.
DR Ensembl; ENSSTOT00000012540.2; ENSSTOP00000011238.2; ENSSTOG00000012540.2.
DR Ensembl; ENSSTOT00000039279.1; ENSSTOP00000030832.1; ENSSTOG00000033899.1.
DR eggNOG; KOG0867; Eukaryota.
DR GeneTree; ENSGT00940000162786; -.
DR HOGENOM; CLU_011226_2_0_1; -.
DR OMA; INDNGYK; -.
DR TreeFam; TF325759; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0004364; F:glutathione transferase activity; IEA:UniProtKB-EC.
DR CDD; cd03183; GST_C_Theta; 1.
DR CDD; cd03050; GST_N_Theta; 1.
DR Gene3D; 1.20.1050.10; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR004045; Glutathione_S-Trfase_N.
DR InterPro; IPR004046; GST_C.
DR InterPro; IPR040077; GST_C_Theta.
DR InterPro; IPR040075; GST_N_Theta.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43917; -; 1.
DR PANTHER; PTHR43917:SF4; GLUTATHIONE S-TRANSFERASE THETA-2-RELATED; 1.
DR Pfam; PF00043; GST_C; 1.
DR Pfam; PF02798; GST_N; 1.
DR SFLD; SFLDG01153; Main.4:_Theta-like; 1.
DR SFLD; SFLDG00358; Main_(cytGST); 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS50405; GST_CTER; 1.
DR PROSITE; PS50404; GST_NTER; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT DOMAIN 1..82
FT /note="GST N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50404"
FT DOMAIN 88..230
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
SQ SEQUENCE 244 AA; 28041 MW; BFDBA72328ECEB0E CRC64;
MGLELYLDLL SQPCRAVFIF AKKNGIPFQL RTVQLLKGQN CSKEFLQINS LQRVPVLKDG
DFILTESSAI LIYLSCKYQV ADHWYPSDLQ TRSQIQEYLG WHAYNIRSIF GVTLWVRVLA
PLIGIQVPEE KVNRNRTYMD HALQQLESKF LGDKPFLVGQ QVSLADLMLL EELIQPVAVG
YDVFVGRPRL AAWRGRIEAF LDTELWQEAH GPIFNILEQM AKKTLPVPPP ETQKNMLFRI
SKIP
//
