ID I3MNR4_ICTTR Unreviewed; 1371 AA.
AC I3MNR4;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=ATPase family AAA domain containing 2 {ECO:0000313|Ensembl:ENSSTOP00000013336.2};
GN Name=ATAD2 {ECO:0000313|Ensembl:ENSSTOP00000013336.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000013336.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000013336.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01001661; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 43179.ENSSTOP00000013336; -.
DR Ensembl; ENSSTOT00000014887.2; ENSSTOP00000013336.2; ENSSTOG00000014877.2.
DR eggNOG; KOG0732; Eukaryota.
DR GeneTree; ENSGT00550000074694; -.
DR HOGENOM; CLU_001448_3_2_1; -.
DR InParanoid; I3MNR4; -.
DR OMA; RKMYFSD; -.
DR TreeFam; TF314783; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:Ensembl.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:Ensembl.
DR CDD; cd05528; Bromo_AAA; 1.
DR CDD; cd19517; RecA-like_Yta7-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR045199; ATAD2-like.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23069; AAA DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23069:SF4; ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00674; AAA; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT DOMAIN 988..1043
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 215..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1162..1263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..268
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1162..1189
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1190..1205
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1228..1249
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1371 AA; 156093 MW; 984150F89A47CDE9 CRC64;
MVVLRSSLEL HSRSTASATD SLDLSSEFLS LEQMGRRRLR SAGAAEKAAV TAAASGDGSS
VKEVETYHRT RALKSLRKNA QTSSDSSFDK NMEITEKHAN GRHFTRQLAR QQANKKKEEC
KEDKVIPVTR SLRTRNIVQT TEHLHEENGD VEVRRSCRIR SRYSTVNQSV LFDKLITNTA
EAVLQKMDDM KKMRRQRMRE LEDLGVFNET EKGNLNMYTR GKQKGIQRTD EETTDNQEGS
VESSEEGEDQ EDEDDDEEDD EDEEDGEEDN QKRYYLRQRK ATVYYQAPLE KPRHQRKPNI
FYSGPASPAR PRYRLSSAGP RSPYCKRMNR RRHAIHSSDS TSSSSSEDEQ HFERRRKRSR
NRAINRCLPL NFRKDELRGI YKDRMKIGAS LADVDPMQLD SSVRFDSVGG LSKHIAALKE
MVVFPLLYPE VFEKFKIQPP RGCLFYGPPG TGKTLVARAL ANECSQGDKR VAFFMRKGAD
CLSKWVGESE RQLRLLFDQA YQMRPSIIFF DEIDGLAPVR SSRQDQIHSS IVSTLLALMD
GLDSRGEIVV IGATNRLDSI DPALRRPGRF DREFLFSLPD KDARKEILKI HTRDWNPKPL
DVFLEELAEN CVGYCGADIK SVCAEAALSA LRRRYPQIYT TSEKLQLDLS SINISAKDFE
VAMQKMIPAS QRAVTSPGQA LSAIVKPLLQ STVQKILEAL QRVFPHVDMR TNKALDSDIS
CPLLESDLTY SDDDIPSVYE NGLSQKSNKA KENFNFLHLN RNACYQPMSF RPRILIVGEP
GFGQGSHLAP AVIHALEKFT VYTLDIPVLF GVSATSPEET CAQMIREAKR TAPSIIYVPH
IHLWWEIVGP TLKATFTTLL QNIPSFAPVL LLATSDKSHS DLPEEVQELF IHDYGEIFNV
QLPGKEERTA FFEDLILKQA AKPPISKKKA VLQALEVLPV APPPEPRPLT ADEVKRLEEQ
EEDTFRELRI FLRNVTHRLA IDKRFRVFTK PVDPDEVPDY ITVIKQPMDL SSVISKIDLH
KYLTVKDYLR DIDLICSNAL EYNPDRDPGD RLIRHRACAL RDTAYAIIKE ELDEDFEQLC
EEIQESRKKR GCSSSKYAPS YYHVMPKQNS TLAGDKRSDL EQNEKLKASS IPVACSTPAQ
LKRKIRKKSK WYLGTITKRR KISQAKDDSH NAIDDKIESD IEETQDTSVD HNETGNTGES
SIEENEKQQS ASESKRELGN NSSTYNIEKE LEESKNATPS TELRKDKVVC NGDPSNSQII
GISDENEGKE MCVLRMTRAR RSQVEQQQLI SVEKALAILS QPTPTLVVDH DRLKNLLKTV
VKKSKEYNIL QLENLYAVIS QCIYQHRRDY DKTTLIQKME QEVENFSCSR S
//
