ID   I3MQB9_ICTTR            Unreviewed;      1116 AA.
AC   I3MQB9;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 2.
DT   27-MAR-2024, entry version 59.
DE   SubName: Full=BAI1 associated protein 3 {ECO:0000313|Ensembl:ENSSTOP00000014116.3};
GN   Name=BAIAP3 {ECO:0000313|Ensembl:ENSSTOP00000014116.3};
OS   Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS   tridecemlineatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC   Xerinae; Marmotini; Ictidomys.
OX   NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000014116.3, ECO:0000313|Proteomes:UP000005215};
RN   [1] {ECO:0000313|Proteomes:UP000005215}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Assembly & Analysis Group;
RG   Computational R&D Group;
RG   and Sequencing Platform;
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT   "The Draft Genome of Spermophilus tridecemlineatus.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSTOP00000014116.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the unc-13 family.
CC       {ECO:0000256|ARBA:ARBA00005823}.
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DR   EMBL; AGTP01095372; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005337910.1; XM_005337853.2.
DR   AlphaFoldDB; I3MQB9; -.
DR   Ensembl; ENSSTOT00000015775.3; ENSSTOP00000014116.3; ENSSTOG00000015767.3.
DR   GeneTree; ENSGT00730000110939; -.
DR   HOGENOM; CLU_003295_2_0_1; -.
DR   TreeFam; TF315526; -.
DR   Proteomes; UP000005215; Unassembled WGS sequence.
DR   GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   CDD; cd08676; C2A_Munc13-like; 1.
DR   CDD; cd04009; C2B_Munc13-like; 1.
DR   Gene3D; 1.10.357.50; -; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 2.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR010439; MUN_dom.
DR   InterPro; IPR014770; Munc13_1.
DR   InterPro; IPR014772; Munc13_dom-2.
DR   PANTHER; PTHR45999:SF1; BAI1-ASSOCIATED PROTEIN 3; 1.
DR   PANTHER; PTHR45999; UNC-13-4A, ISOFORM B; 1.
DR   Pfam; PF00168; C2; 3.
DR   Pfam; PF06292; MUN; 1.
DR   SMART; SM00239; C2; 2.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR   PROSITE; PS50004; C2; 2.
DR   PROSITE; PS51258; MHD1; 1.
DR   PROSITE; PS51259; MHD2; 1.
PE   3: Inferred from homology;
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT   DOMAIN          141..300
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          592..713
FT                   /note="MHD1"
FT                   /evidence="ECO:0000259|PROSITE:PS51258"
FT   DOMAIN          817..925
FT                   /note="MHD2"
FT                   /evidence="ECO:0000259|PROSITE:PS51259"
FT   DOMAIN          939..1065
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   REGION          22..41
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          195..215
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..38
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1116 AA;  125085 MW;  705CD9E8B0E18476 CRC64;
     MSTLLEIKSS VLRQVQVCPS FRRKTEQEPT STSVDLQEPA TGAWKPGDGV EFFAHMRLIL
     KKGEGRQGLP CPEVLLRSGS PAPAEPVDSN RGLRALTQEE VEMLYEEALY TVLHRAGTMS
     PDQVDDEEVL LAYLQQVFGT NPEQHAEAIE RVKKAKAPTY ALKVSVMRAK NLLAKDPNGF
     SDPYCMLGIL PASGTPREQS GQKEQRFSFR KGSKRSGPLP AKCIQVTEVK SSTLNPVWKE
     HFLFEIEDVS TDQLHLDIWD HDDDVSLAEA CRKLNEVIGL KGMSRYFKQI VKSARANGTA
     GPTEDHTDDF LGCLNIPVRR DTIMSQRGRF GFLSYLLLLS RVLRFEHRVE EPNSSSWHGE
     LSGPGTTILC LHGAQSNLSP LQLAVLHWQV SSRHHQTRTL DYGYLLGLLE DMQAHWEEAP
     LLPQEQEESL ADSFSAFSEF GLRLLRQLRD YFPATNSTAV YRLELLLKCL DKLQLFQPSF
     EICPFETELN MDIAAALKRG NREWYDRLLS AKSPRELPGP QRLAGLVELA DVIYEDLQAC
     YGIYASLFHG ILKVDFFTLT FRQLERLVAE EAWVLTEELS PKMTLQVASG LFELYLTLAD
     IQHFWSYIPG RDSRSLALAG IHTPFLPAVK LWLQVLRDQS KWRLQGAVDV DTLEPVDASS
     RHSSSAATAS LCFSHIQELW VRLAWPDPAQ AQGLGTQLSQ DLCEAALFYT ELLRKKVDAQ
     PGAAGEAVSE PLCVVLNNVE LVRRASGQAL RGLAWPEGAL GLEGVLPRPL LSCIQALEED
     LHREAHTVTA HLTSKMVADI RKYVQHISLS PDSIQNDEAV APLMKYLDEK LALLNASLVK
     ENLSRVLEAL WELLLQAILQ ALGANSDVSA DFYGRFHFTL EALVSFFHAE GQGLPLESLR
     DGSYKRLEEE LRLHKCSTRE CIEQFYLDKL KQRSLEQNRF GRLSVRCHYE AAEQRLAVEV
     LHAADLLPLD ANGLSDPFVI VELGPPHLFP LVRSQRTQVK ARTLHPVFDE LFHFSVPAEA
     CRHRGACVLF TVMDHDWLST NDFAGEAALS LGSVSGIARP QVGAGSRAGQ PITLHLRRPR
     AQVRSALRML EGRTNKEAQE FVKKLKELEK CMEADP
//