ID I3N0T4_ICTTR Unreviewed; 1654 AA.
AC I3N0T4;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=PHD and ring finger domains 1 {ECO:0000313|Ensembl:ENSSTOP00000017980.2};
GN Name=PHRF1 {ECO:0000313|Ensembl:ENSSTOP00000017980.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000017980.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000017980.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01115377; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01115378; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005341677.1; XM_005341620.2.
DR Ensembl; ENSSTOT00000029569.2; ENSSTOP00000017980.2; ENSSTOG00000023124.2.
DR eggNOG; KOG0825; Eukaryota.
DR GeneTree; ENSGT00950000183205; -.
DR HOGENOM; CLU_003222_0_0_1; -.
DR TreeFam; TF332183; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16635; mRING-HC-C3HC3D_PHRF1; 1.
DR CDD; cd15536; PHD_PHRF1; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR047157; PHRF1-like.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR12618; PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR12618:SF20; PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 111..152
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 186..236
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 1..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 330..395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 450..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 837..861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 914..1227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1282..1356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1418..1487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1534..1562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..79
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..384
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..478
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..596
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 615..668
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 700..717
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 734..767
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 843..861
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 947..961
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1005..1030
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1031..1052
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1060..1086
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1149..1199
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1288..1303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1428..1444
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1535..1549
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1654 AA; 178960 MW; EC78C108D32CDE80 CRC64;
MDDDSLDQPV AQSPCPDGCP RVGPADLTSS AGLEESSDGH SGDSEDDTGS EHGDCTDRED
EEAASEEEDP EDGSGSQDSE DEVESLVAAT DAQGKLEARS TLSSDEDVES CPICLNVFRD
QAVGTPETCA HYFCLDCIVE WSRNANSCPV DRTIFKCICI RAQFGGKILK KIPVESTRAH
EEEEDPTFCE VCGRSDREDR LLLCDGCDAG YHMECLEPPL REVPVDEWFC PECAVPSTAS
AADAGPVSEE EVSQLLADVV PTTSRLRPNT GRTRAIARTR QSERVRATVN RNRISTARRV
QHVPRYLMSA LLDETIEAVA TGLSTAVYQR PLTPRGPVRR KRKTGRRKKV PGRRKTQSRS
STKSKGASTR SKKRQRHGKR RKGRVPKAQN EVTARSRIAR TLGLCRPVRG TCMPSVYKPV
DPSLGLMRAD IGAASLSLFG DPYELDPFDS EELSANPASP LSTKRRVLSR SALQSHQPVA
RPVSVGLSRR PLPATQEESV EEAPLPDLLG SILSGQSLLM MSSADVVIHR DGSLSAKRAA
PISLQRNSVG VSGGEERSRP RDSLQTGVPS SGIPASRLTG DRPQSSGLSG QARSAPHNPA
CSAGVPVRPG ASPAPGSGQA QNLSNGSGPS LRQSGSPWFN GTSKQSLSLG SASSKISSSC
SNSPLGSVAL GHTPKPPPRR TAISELPRIP KIQRDGTGSR QDAAPPQGQS VEIPSTCISR
LTGREGPGQP AQGRAENEPS NRGPQNSGSH TGSSRPPAPS SHGSLASLGP SRGKGLGSTF
ESFRINIPGN TAHCSRLSSP GFCNTFRPVD SKVQRKENPS PLFSIKKTKQ LKSEIYDPFD
PTVSDSSPPS SSPESLGPSL LPSEITRTIS INSPKAPAFQ AVRCVTSYTV ESVFETEAEP
PGTPVSSVLK VRGEGATEGA SDVEQEELGE EPTESRGPAA RAQRPSPQDP WDDEDGAAHG
TFFGSEERMV TCVTILEPEA SPSPDAPQAA THRIVELRAP SRSRSTSSSR KKAKRKRGTK
EHRRTRSRTH SGSRDRTSHS ASPSVEEHSR GRQAKAKHRR SSSDRASSQE RAKRRKAQDR
SRERRRDSRG RGRRRSRSRS GSPASSSCER YGSRRKRRRQ SGSRSRGRDC SPPSSLERAR
RHKHQRERSR ERPNKESTGR ARERRKWRSR SPSSEHRARE PRQPRSREKR PRSLERKGTA
KEASPVPALQ QELRQGGDHS VTPPVPAEAG IVAEVGVSGQ VLPQAPPVLE EPAECAPEDL
DYGASVEAGH VFEDFSSEAI FIQLDDMSSP PSPESTDSSP ERSFLPNPAR PPAPQAQDPT
LAAIQREVSL IHSEDAVHPL PPAEGPPEQR PLRPDLAENT VMAPSALGVA PVEEDSPSGS
GRVCQVARPE EAAVQAPLLR SRALVKRVTW NLQESEGAAV VPDRGSRTPL HRPQRPREEA
WDTEDGGPIG DTQALISELP PPSHILLEPG FPDMNPSQVY SSNMPPGLAQ PPSIPPYTLI
SQPSVQFILQ GSLPLAGCGV AQSVAPVPTA LATASEPAGQ ASTTDLEERT ATPRPAAEKT
RKEEYMKKLH MQERAVEEVK LAIKPFYQKR EVTKEEYKDI LRKAVQKICH SKSGEINPVK
VANLVKAYVD KYRHMRKHRK TEAGEEPPAQ GTEA
//
