ID I3N457_ICTTR Unreviewed; 1276 AA.
AC I3N457;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Uncharacterized LOC101976998 {ECO:0000313|Ensembl:ENSSTOP00000019153.2};
GN Name=LOC101976998 {ECO:0000313|Ensembl:ENSSTOP00000019153.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000019153.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000019153.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01043183; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01043184; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01043185; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01043186; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01043187; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3N457; -.
DR STRING; 43179.ENSSTOP00000019153; -.
DR Ensembl; ENSSTOT00000021636.2; ENSSTOP00000019153.2; ENSSTOG00000028345.2.
DR eggNOG; KOG3528; Eukaryota.
DR GeneTree; ENSGT00530000064469; -.
DR HOGENOM; CLU_005672_0_0_1; -.
DR InParanoid; I3N457; -.
DR OrthoDB; 2913694at2759; -.
DR TreeFam; TF333483; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR47644; AGAP008221-PA; 1.
DR PANTHER; PTHR47644:SF1; SEA DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00169; PH; 2.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00233; PH; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50003; PH_DOMAIN; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT DOMAIN 943..1018
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1030..1132
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 1157..1254
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 22..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 347..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 416..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 503..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 753..774
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 833..883
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..88
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..120
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..439
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 440..458
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 849..863
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 864..883
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1276 AA; 143645 MW; 64E8F0741B6441EE CRC64;
MIYEGFTRAV ITEDLQLSKM RRKRRRGYKK KKALNTTVCT SQPSGQACQK NTEELEKEVE
GDTSKAAFHQ TGVLRKSKEN RDEHTSASVN RKQNPSFLPE EKKQPPSDSK IGRGEENDDP
SLAISHQLKK ALPVVVMFKD GEESLSGKIT LQDFPSTVKN CEAENGKFIT EVKCGAFNVQ
VEIKKSIFCK TGAQFPTKKV CPTCHQPFSA RFIRRCYTFR RCFPKHNNTL AEKIKPEVSS
KQGKLARTES PSLKVGIVGK EIKVKYISKK QNVIINITHP KRRGKITKYR TIPSNLTTKE
SFRSPLQSDI KYPEKQQLEK KHQSAGASPP VECTIQKENS DTVLVSLTST PKREKNKSDT
LSSVSDDSEV ESAIFQQKAF KICQNNPKKK HFSGADALQK NILPTSHDTL KTTRLNNTHL
SKTPFEDPKD VDKERKNNSA VPENITPESH TQQSTDGTNH LLSTVTNIIP IQDVSDSDFC
SLSSLSIQLL GEKATSIYCK GNKTSSTESC ENSNSKSFSS SQNALKSSTS FSPSHLATRH
LEPKDTLGHT FSFNHCAEFV IDHEKEHGDM TETDIKKAII HGDSCANTQQ LLETKSTQSP
TLIPASCSSL AVEDSLHNIS HTTVGWDQTE AQKNHPETVA PSRTKVSVMS FITDKFEQRL
ITQNDKEHTV DSNCPLGMRT PKESPSFLEN IEKEKCQLIP VIMNACHRGF EDLPSENHDE
NCFKMDFPPN TAESSYKVCV TDKLFLIQKT LNSDADQSGN QDKESLELTS FQQEPGECQR
IALTRQDSEG DEDKNDSKEN YYHQIDILLS PQKQKALKDQ NLEISSLGKF SQESALRGGR
ASDGSQEEAI DQWARRRQQF REGRRCNSTG GSSFTSNITE GSITSEDGRS LDFGFRVDTE
EKGFYTENFH SAAWVFRGDD GNPEDSPRCL SKKPRPVAVR ERTVRLFKGT GDYPWGFRIQ
FSKPIMVTEV DTNSAAEEAG LLIGDVVLSV NGTEVTSVEH AEAVHLARKG PDILTLVVGS
DISHCPNTPR PTCRGYLHKR THSGFMKGWR KRWFVLKHDG CLHYYKHKKD EGKWPPLEVI
KLEGAEVGID SSLGKSFVFN CVPPPGNRSL CLCATSNQEM KRWLEAMEKA AHPIHQNHVW
EDVTLHNSSL PPLAIKNPEC LGLLHQLDRS TDLWVQHYCI LKDGCLYFYD SIRSTRASGG
LYLQGYRVSE QTHSFKQSVI ELKPPSEEFK TFYLCAENKT ENQRWITALQ MSIKKWIPLH
QAIQDFMNRP LEETRM
//
