ID I3NBL7_ICTTR Unreviewed; 1446 AA.
AC I3NBL7;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Ninein like {ECO:0000313|Ensembl:ENSSTOP00000021764.2};
GN Name=NINL {ECO:0000313|Ensembl:ENSSTOP00000021764.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000021764.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000021764.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGTP01078168; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01078169; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01078170; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01078171; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01078172; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005334669.1; XM_005334612.2.
DR STRING; 43179.ENSSTOP00000021764; -.
DR Ensembl; ENSSTOT00000021178.2; ENSSTOP00000021764.2; ENSSTOG00000014411.3.
DR eggNOG; ENOG502R2VA; Eukaryota.
DR GeneTree; ENSGT00660000095541; -.
DR InParanoid; I3NBL7; -.
DR OrthoDB; 2880167at2759; -.
DR TreeFam; TF325139; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR18905; NINEIN; 1.
DR PANTHER; PTHR18905:SF12; NINEIN-LIKE PROTEIN; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT DOMAIN 7..42
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 233..268
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 583..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 902..932
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1029..1057
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 391..421
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 463..518
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 552..579
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 616..668
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1097..1302
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1394..1428
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 906..921
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1446 AA; 163887 MW; D14FA23179B97CE7 CRC64;
MDEEENHYVS QLREVYNSCD TTGTGFLDRD ELTQLCCKLH LEKQLPILLQ TLLGSNHFAR
VNFEEFKEGF VAVLSSTVGV GPLDEESSSL ESAASCAVPP KYVSGSKWYG RRSRPERWDS
AAEAKYVPEQ QAKASLKSQL RRSASLESVE SLKSDEEAES AKETQNELFE AQGQLQTWSS
EVFGSSQKPC SPSLDSPERQ VRGIWEELGV GSSGHLNEQE LAVVCQSIGL HGLEKEELED
LFNKLDQDGD GRVSLAEFQV GLFSHEPASL LESSTLLKSS KPWSHCQVPT ENGCHPTPTT
SSLVSVCSGL RFFSNVDDGS GFAFPEQIIT TWAQEGIQNG REILQSLDFS MDEKVNLLEL
TWALDNELLT VDGVVQQAAL ACYRQELSYH LTQVEQLVQE RDKARQDLER AEKRNLEFVK
EMDDCHSALE QLTEKKIKNL EEGYRGRLSL LRSEVEMEQE LIWEQACRQK AALEQDVSRL
RAEEASLHEK LTLALKENSR LQKEIVEVVE KLSDSEKLVL KLQNDLEFVL KDKLEPQNME
LPSQEEQFAV LLKEYELKCR DLQDCNDELQ AELEGLRAQL PESWQSPSED LGTHGQRVSG
RGPAGILSVG DSTPVNIETE IMMEQVKERY QDLKIQLETK VNYYEMEIEV MQRNFQKERK
EMEQAHQLEV CTLESQKADL EALYTKSQEV ILGLREQLQD ATHGPEPGQT GMEQCCAQVL
CGLAQQLKEE LQLRHQNQLQ QIRKEAEDVL TQKLSWLEAQ HVARCERLSL QHQSEKDRLL
QTHLWRLREL VAQLDLEKEQ QGEREKEILT RCQKQQMKLQ AAMSEEQAQI CRSMALEKEK
LEHTYRKQVE GLAQEAEALR ALLNDGTTVT GSEQGGIPGL TSLCLGGEQP LAQLDLNTDG
EMRELAGDTP GQRRTEGRDL PSQPRCVDTT QSPTPVLVSR ESLKSFSLGE NCQGPLSAGE
VASVPLEKRS YMQPCEGNKG AIAEEPVPSA RAPMGLGQAD AQELPVLATE GIAWLAQPQT
LEPWHSPATL EEQASSLSRD PAPESGPGQV FEGMSRGGDD ALETWLEHSQ EAARWGSSLL
HSKLPDPQQP GLECLTALEE TEAKMALEKE KSDMRNKLLQ LEDVVRALEK EADSRENDRI
EFQRISEENM LLKNDLGKIQ QELEAAESTN DAQRKEIEDL KRDKEKTCLE MEELNIQIQK
YKDELSQLNC RVLQLEGDAS THQALKEKNH IAIQLLRQRL EEARRREEQQ DNQIKKLEVE
LQHVNQECQN LRLSQSELKV SLEESQEQLH SAHLRLKAAQ SQHAQEVQHL QEQKSQLVPR
ARVTELQHLL SVQEKEAGRL LDAQREEHER QMKTKEGQAK EAEMCLQNVE WLLQEKVDEL
REQFKKNTKS DLLLKELYVE NAHLMKALQV TEEKQRGAES KNRILEEKVH ALNKLINKIA
LASLSV
//
