ID I3T8Z7_MEDTR Unreviewed; 367 AA.
AC I3T8Z7;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Caffeic acid O-methyltransferase {ECO:0008006|Google:ProtNLM};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:AFK48989.1};
RN [1] {ECO:0000313|EMBL:AFK48989.1}
RP NUCLEOTIDE SEQUENCE.
RA Krishnakumar V., Cheung F., Xiao Y., Chan A., Moskal W.A., Town C.D.;
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; BT149195; AFK48989.1; -; mRNA.
DR AlphaFoldDB; I3T8Z7; -.
DR ExpressionAtlas; I3T8Z7; differential.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR012967; Plant_MeTrfase_dimerisation.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11746:SF221; CAFFEIC ACID O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11746; O-METHYLTRANSFERASE; 1.
DR Pfam; PF08100; Dimerisation; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 2: Evidence at transcript level;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 40..86
FT /note="Plant methyltransferase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF08100"
FT DOMAIN 143..346
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 273
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 367 AA; 40633 MW; 357CCFAAF95023AA CRC64;
MSSNSNDKVN HVVETHTPQI DDNETLSAMV LGSNLVFPAV LNAAIQLNLF EIIGDGFKSA
IEIASNLPTQ HSDLPNRLDR MLRLLASYSL LSISTRTNDD GSIVRVFGIT PSGKYFCYDE
NSDHGYVGSF TSFMCHPALI GSWLNFKDAV LDPEIDLFKK VNGISKYEYF GKDPQINQIF
NKSMTNMTKI HMKEILEKYK GYEGISTLVD IGGGNGQTLK MIIEKYPSIK GINFDLPQVI
ENASPIPGIE HVGGSMFESV PQGDAIMLKA VCHNWSDEKC IEIFSNCYKA LPQNGKVILV
ELALPECPEP TNASRFASII DNIMFINAGG KERTPKEYEI FAQRSGSSRL EVVCCAFSII
GVMEIYK
//
