ID I3TIF8_TISMK Unreviewed; 267 AA.
AC I3TIF8;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=NAD-dependent epimerase/dehydratase {ECO:0000313|EMBL:AFK52546.1};
GN Name=hldD {ECO:0000313|EMBL:AFK52546.1};
GN OrderedLocusNames=TMO_0707 {ECO:0000313|EMBL:AFK52546.1};
OS Tistrella mobilis (strain KA081020-065).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Geminicoccales;
OC Geminicoccaceae; Tistrella.
OX NCBI_TaxID=1110502 {ECO:0000313|EMBL:AFK52546.1, ECO:0000313|Proteomes:UP000005258};
RN [1] {ECO:0000313|EMBL:AFK52546.1, ECO:0000313|Proteomes:UP000005258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KA081020-065 {ECO:0000313|EMBL:AFK52546.1,
RC ECO:0000313|Proteomes:UP000005258};
RX PubMed=22458477; DOI=10.1021/ja301735a;
RA Xu Y., Kersten R.D., Nam S.J., Lu L., Al-Suwailem A.M., Zheng H.,
RA Fenical W., Dorrestein P.C., Moore B.S., Qian P.Y.;
RT "Bacterial biosynthesis and maturation of the didemnin anti-cancer
RT agents.";
RL J. Am. Chem. Soc. 134:8625-8632(2012).
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DR EMBL; CP003236; AFK52546.1; -; Genomic_DNA.
DR RefSeq; WP_014744226.1; NC_017956.1.
DR AlphaFoldDB; I3TIF8; -.
DR STRING; 1110502.TMO_0707; -.
DR KEGG; tmo:TMO_0707; -.
DR eggNOG; COG0451; Bacteria.
DR HOGENOM; CLU_1041841_0_0_5; -.
DR Proteomes; UP000005258; Chromosome.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR PANTHER; PTHR43245:SF23; BLR5423 PROTEIN; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005258}.
FT DOMAIN 41..187
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 267 AA; 29034 MW; BDC65BF0D5649978 CRC64;
MRILVFGGGS LLASAFTGTA ISGGSFRIAR HSDIDAPDLM DGIDVVVNFA RHPDDMRLPH
DPERDVDLRL ARRMAGTQAR YVMLSSRKVY SADAQQDAAE DAPLSGLDVY GCNKVAAEAA
LRDLLPADRL TVLRIGNVIG PERIPGRRSF MGFMLNTLAD TGEIVFDMSP FVSRDFVTVE
HFAAQLGRIV ELGLTGTYNL SSGTGIMCGE LALAVIRGHG RGQLRIIDPR HADAFRLDVS
RLVRETGLRQ TADEIISYCY NLGRALG
//
