ID I3TLU1_TISMK Unreviewed; 350 AA.
AC I3TLU1;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Oxidoreductase, zinc-binding dehydrogenase family {ECO:0000313|EMBL:AFK53729.1};
GN OrderedLocusNames=TMO_1890 {ECO:0000313|EMBL:AFK53729.1};
OS Tistrella mobilis (strain KA081020-065).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Geminicoccales;
OC Geminicoccaceae; Tistrella.
OX NCBI_TaxID=1110502 {ECO:0000313|EMBL:AFK53729.1, ECO:0000313|Proteomes:UP000005258};
RN [1] {ECO:0000313|EMBL:AFK53729.1, ECO:0000313|Proteomes:UP000005258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KA081020-065 {ECO:0000313|EMBL:AFK53729.1,
RC ECO:0000313|Proteomes:UP000005258};
RX PubMed=22458477; DOI=10.1021/ja301735a;
RA Xu Y., Kersten R.D., Nam S.J., Lu L., Al-Suwailem A.M., Zheng H.,
RA Fenical W., Dorrestein P.C., Moore B.S., Qian P.Y.;
RT "Bacterial biosynthesis and maturation of the didemnin anti-cancer
RT agents.";
RL J. Am. Chem. Soc. 134:8625-8632(2012).
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DR EMBL; CP003236; AFK53729.1; -; Genomic_DNA.
DR RefSeq; WP_014745407.1; NC_017956.1.
DR AlphaFoldDB; I3TLU1; -.
DR STRING; 1110502.TMO_1890; -.
DR KEGG; tmo:TMO_1890; -.
DR eggNOG; COG0604; Bacteria.
DR HOGENOM; CLU_026673_3_1_5; -.
DR Proteomes; UP000005258; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR48106; QUINONE OXIDOREDUCTASE PIG3-RELATED; 1.
DR PANTHER; PTHR48106:SF13; QUINONE OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Reference proteome {ECO:0000313|Proteomes:UP000005258}.
FT DOMAIN 30..347
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 350 AA; 35654 MW; 8E720C1368011D99 CRC64;
MTTPPTPLSP GSPTTHLPDR ATVMHVTHPG GPDVLAPATV PLKRPGPGEV LMATRAIGVN
HLDLYYRDGT LPLEGGGVDI PGLASVGEVL AIGPGVDRFA PGDRIAHAGP PLGAYATHRV
LPVGRVVRFP HMIPWEVGAA ALFPGIAVHM MIYGLGLRLD GRVVLVRGAG GGVGLILVRW
AAAMGARVIA SVATRAKAEA VQEAGAERVV VGTGATALAD AGRAAAELTG GAGVHIVFDG
LGGPDFAKLA ALVRPFGRIV SFGQVAGPIP PVDVGVLGPM RALGLDRPGV FAYIADRERL
REATSALFTA LVEGLLSPTV AGVLPLSRAG DAHARLEART VTGSLVLIPD
//
