ID I3TSQ5_TISMK Unreviewed; 340 AA.
AC I3TSQ5;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Putative Aminoglycoside phosphotransferase {ECO:0000313|EMBL:AFK55793.1};
GN OrderedLocusNames=TMO_a0390 {ECO:0000313|EMBL:AFK55793.1};
OS Tistrella mobilis (strain KA081020-065).
OG Plasmid pTM1 {ECO:0000313|EMBL:AFK55793.1,
OG ECO:0000313|Proteomes:UP000005258}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Geminicoccales;
OC Geminicoccaceae; Tistrella.
OX NCBI_TaxID=1110502 {ECO:0000313|EMBL:AFK55793.1, ECO:0000313|Proteomes:UP000005258};
RN [1] {ECO:0000313|EMBL:AFK55793.1, ECO:0000313|Proteomes:UP000005258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KA081020-065 {ECO:0000313|Proteomes:UP000005258};
RC PLASMID=Plasmid pTM1 {ECO:0000313|Proteomes:UP000005258};
RX PubMed=22458477; DOI=10.1021/ja301735a;
RA Xu Y., Kersten R.D., Nam S.J., Lu L., Al-Suwailem A.M., Zheng H.,
RA Fenical W., Dorrestein P.C., Moore B.S., Qian P.Y.;
RT "Bacterial biosynthesis and maturation of the didemnin anti-cancer
RT agents.";
RL J. Am. Chem. Soc. 134:8625-8632(2012).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003237; AFK55793.1; -; Genomic_DNA.
DR RefSeq; WP_014747470.1; NC_017957.2.
DR AlphaFoldDB; I3TSQ5; -.
DR KEGG; tmo:TMO_a0390; -.
DR PATRIC; fig|1110502.3.peg.4039; -.
DR HOGENOM; CLU_007526_0_1_5; -.
DR Proteomes; UP000005258; Plasmid pTM1.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05154; ACAD10_11_N-like; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR041726; ACAD10_11_N.
DR InterPro; IPR002575; Aminoglycoside_PTrfase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR47829:SF1; AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR47829; HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED; 1.
DR Pfam; PF01636; APH; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Plasmid {ECO:0000313|EMBL:AFK55793.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005258};
KW Transferase {ECO:0000313|EMBL:AFK55793.1}.
FT DOMAIN 32..252
FT /note="Aminoglycoside phosphotransferase"
FT /evidence="ECO:0000259|Pfam:PF01636"
SQ SEQUENCE 340 AA; 37782 MW; 110A9AB70D8FFAD5 CRC64;
MSITPETTTP DTEALEAWFA DHVPGRHGRL ALERFAGGQS NPTFRIRSEA GTYVLRRKPL
GEVLPSAHAV DREFRVLAAL QGTGVPVPPV HALCTDPAVF RSMFYVMDFV PGRIFWDPRL
PDLSPAERGA IFSSMNDAIA RIHALDPDAI GLGDHGRRGN YVERQIARWT RQYRASETVA
NPAMERLIQW LPEHVPAEDD TRLVHGDYRL DNVIIHPTEP RVVAVLDWEL STLGNPLADF
AYHMMTWRIA PGLFRGLAGT DFAAAGIPDE RAYLEMWLAR TGFAPSPSWD VYVVFRLAAI
LQGIARRAQD GTAANADAEE VGRKAVPLAD LAWSFAEKIR
//
