ID   I3TTF1_TISMK            Unreviewed;       293 AA.
AC   I3TTF1;
DT   05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2012, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:AFK56039.1};
GN   Name=yeaT {ECO:0000313|EMBL:AFK56039.1};
GN   OrderedLocusNames=TMO_b0031 {ECO:0000313|EMBL:AFK56039.1};
OS   Tistrella mobilis (strain KA081020-065).
OG   Plasmid pTM2 {ECO:0000313|EMBL:AFK56039.1,
OG   ECO:0000313|Proteomes:UP000005258}.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Geminicoccales;
OC   Geminicoccaceae; Tistrella.
OX   NCBI_TaxID=1110502 {ECO:0000313|EMBL:AFK56039.1, ECO:0000313|Proteomes:UP000005258};
RN   [1] {ECO:0000313|EMBL:AFK56039.1, ECO:0000313|Proteomes:UP000005258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KA081020-065 {ECO:0000313|Proteomes:UP000005258};
RC   PLASMID=Plasmid pTM2 {ECO:0000313|Proteomes:UP000005258};
RX   PubMed=22458477; DOI=10.1021/ja301735a;
RA   Xu Y., Kersten R.D., Nam S.J., Lu L., Al-Suwailem A.M., Zheng H.,
RA   Fenical W., Dorrestein P.C., Moore B.S., Qian P.Y.;
RT   "Bacterial biosynthesis and maturation of the didemnin anti-cancer
RT   agents.";
RL   J. Am. Chem. Soc. 134:8625-8632(2012).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
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DR   EMBL; CP003238; AFK56039.1; -; Genomic_DNA.
DR   AlphaFoldDB; I3TTF1; -.
DR   KEGG; tmo:TMO_b0031; -.
DR   PATRIC; fig|1110502.3.peg.4289; -.
DR   HOGENOM; CLU_039613_16_4_5; -.
DR   Proteomes; UP000005258; Plasmid pTM2.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08422; PBP2_CrgA_like; 1.
DR   Gene3D; 3.40.190.290; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30537:SF5; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR TTDR-RELATED; 1.
DR   PANTHER; PTHR30537; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Plasmid {ECO:0000313|EMBL:AFK56039.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005258}.
FT   DOMAIN          2..59
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   293 AA;  31071 MW;  12D4CA2BFA77D1BC CRC64;
     MIDLNDVAVL VEAVAAGSLA GAARRLGIGP MVASRRLAAL EDELGVRLVH RTTRALSLTP
     EGEAFWPYAQ TLLENATDGR AAVRPAASGA AGRLRVTCSV PFARKVVAPM MGGFLRDNPA
     LEVELVASDA VVDIVAQGLD LAIRIAPLRD STLIARRVAP NPRQLVASPA YLAARGTPCR
     VAELADHDCL TTPGTGHWSF SGPAGPLRQR VRGRFTATSI DALQEACIDG LGLTIIADWN
     VRDDLATGRL RVVTLEDGAP EPLTIWAIHP TTRFVPPKVR LFVAALEAHL GAR
//