ID I3TTX5_TISMK Unreviewed; 182 AA.
AC I3TTX5;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=TetR family transcriptional regulator {ECO:0000313|EMBL:AFK56213.1};
GN OrderedLocusNames=TMO_b0205 {ECO:0000313|EMBL:AFK56213.1};
OS Tistrella mobilis (strain KA081020-065).
OG Plasmid pTM2 {ECO:0000313|EMBL:AFK56213.1,
OG ECO:0000313|Proteomes:UP000005258}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Geminicoccales;
OC Geminicoccaceae; Tistrella.
OX NCBI_TaxID=1110502 {ECO:0000313|EMBL:AFK56213.1, ECO:0000313|Proteomes:UP000005258};
RN [1] {ECO:0000313|EMBL:AFK56213.1, ECO:0000313|Proteomes:UP000005258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KA081020-065 {ECO:0000313|Proteomes:UP000005258};
RC PLASMID=Plasmid pTM2 {ECO:0000313|Proteomes:UP000005258};
RX PubMed=22458477; DOI=10.1021/ja301735a;
RA Xu Y., Kersten R.D., Nam S.J., Lu L., Al-Suwailem A.M., Zheng H.,
RA Fenical W., Dorrestein P.C., Moore B.S., Qian P.Y.;
RT "Bacterial biosynthesis and maturation of the didemnin anti-cancer
RT agents.";
RL J. Am. Chem. Soc. 134:8625-8632(2012).
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DR EMBL; CP003238; AFK56213.1; -; Genomic_DNA.
DR RefSeq; WP_014752966.1; NC_017966.1.
DR AlphaFoldDB; I3TTX5; -.
DR KEGG; tmo:TMO_b0205; -.
DR PATRIC; fig|1110502.3.peg.4463; -.
DR HOGENOM; CLU_069356_17_1_5; -.
DR Proteomes; UP000005258; Plasmid pTM2.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR InterPro; IPR049445; TetR_SbtR-like_C.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF226; HTH-TYPE TRANSCRIPTIONAL REPRESSOR RV1474C; 1.
DR Pfam; PF21597; TetR_C_43; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Plasmid {ECO:0000313|EMBL:AFK56213.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005258}.
FT DOMAIN 6..65
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 28..47
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 182 AA; 19549 MW; CDB95D6A3F3E0E55 CRC64;
MRADARKNYD QLLAVARQVI AEEGAEASLR DIARRAGVGL GTLYRHFPTR EALLDALLRN
GFDALARRAA ELEAREDQGA ALATWLREAV AMTHDYRGAI ALMVAAIGDE NSALHGSCTG
LRAAGTRLLH RAQAAGAARA DMDGNDLFAL ISALAWLADQ PPLVPRADHL FDIITGAILT
RQ
//
