ID I3V7X5_HYDOL Unreviewed; 342 AA.
AC I3V7X5;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Transcription factor HoSoxJ2 {ECO:0000313|EMBL:AFK74889.1};
OS Hydra oligactis (Brown hydra).
OC Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC Aplanulata; Hydridae; Hydra.
OX NCBI_TaxID=6088 {ECO:0000313|EMBL:AFK74889.1};
RN [1] {ECO:0000313|EMBL:AFK74889.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=22595987; DOI=10.1093/molbev/mss134;
RA Hemmrich G., Khalturin K., Boehm A.M., Puchert M., Anton-Erxleben F.,
RA Wittlieb J., Klostermeier U.C., Rosenstiel P., Oberg H.H., Domazet-Loso T.,
RA Sugimoto T., Niwa H., Bosch T.C.;
RT "Molecular signatures of the three stem cell lineages in hydra and the
RT emergence of stem cell function at the base of multicellularity.";
RL Mol. Biol. Evol. 29:3267-3280(2012).
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DR EMBL; JQ994227; AFK74889.1; -; mRNA.
DR AlphaFoldDB; I3V7X5; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22028; HMG-box_SoxA_SoxB_SoxG; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR10270:SF161; SOX DOMAIN-CONTAINING PROTEIN DICHAETE-RELATED; 1.
DR PANTHER; PTHR10270; SOX TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267}.
FT DOMAIN 63..131
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 63..131
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 257..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 342 AA; 38271 MW; 5FD5316BCDE60B7C CRC64;
MSSMQHKQLA NDHVTSQSAS AINQTSALQQ NGHYENRTQV TLESNDIKSE PDNKLKNDES
TKIKRPMNPF MIFGCEKRRK LAQVHPRMHN SEISKILGAE WKRMSDYEKS PYIQEAKRLK
EQHSIEYPNY KFKANRRKPR QAIKKERPSF PYAADINTIP PAMKFPYPSP FFQDSMYGTM
YPVMGNSNHP AYSSMYSDFA RQSMSSAGVL RTGSAAPTTT PSAADYYSLN KNASPIAAGN
DYYGTVSSKN EYYSGLHSST SETRAERSSS GSGGDIINLS DRYPSSESRQ FENRYGSSFI
GGPGASGSSV VVPTYTSIQN IPHLNTESPA AYSYSSLYEQ RH
//
