ID I3VR25_THYTR Unreviewed; 910 AA.
AC I3VR25;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Titin {ECO:0000313|EMBL:AFK84949.1};
DE Flags: Fragment;
GN Name=TTN {ECO:0000313|EMBL:AFK84949.1};
OS Thyroptera tricolor (Spix's disk-winged bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Thyropteridae;
OC Thyroptera.
OX NCBI_TaxID=124759 {ECO:0000313|EMBL:AFK84949.1};
RN [1] {ECO:0000313|EMBL:AFK84949.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21940861; DOI=10.1126/science.1211028;
RA Meredith R.W., Janecka J.E., Gatesy J., Ryder O.A., Fisher C.A.,
RA Teeling E.C., Goodbla A., Eizirik E., Simao T.L., Stadler T., Rabosky D.L.,
RA Honeycutt R.L., Flynn J.J., Ingram C.M., Steiner C., Williams T.L.,
RA Robinson T.J., Burk-Herrick A., Westerman M., Ayoub N.A., Springer M.S.,
RA Murphy W.J.;
RT "Impacts of the Cretaceous Terrestrial Revolution and KPg extinction on
RT mammal diversification.";
RL Science 334:521-524(2011).
RN [2] {ECO:0000313|EMBL:AFK84949.1}
RP NUCLEOTIDE SEQUENCE.
RA Meredith R., Janecka J., Gatesy J., Ryder O., Fisher C., Teeling E.,
RA Goodbla A., Eizirik E., Simao T., Stadler T., Rabosky D., Honeycutt R.,
RA Flynn J., Ingram C., Steiner C., Williams T., Robinson T., Burk A.,
RA Westerman M., Ayoub N., Springer M., Murphy W.;
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JQ772106; AFK84949.1; -; Genomic_DNA.
DR AlphaFoldDB; I3VR25; -.
DR CDD; cd00063; FN3; 7.
DR CDD; cd05748; Ig_Titin_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 9.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR14340; MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3; 1.
DR PANTHER; PTHR14340:SF13; TITIN; 1.
DR Pfam; PF00041; fn3; 7.
DR Pfam; PF07679; I-set; 2.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 7.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF49265; Fibronectin type III; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50853; FN3; 7.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 20..114
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 117..210
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 214..298
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 309..403
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 409..503
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 507..603
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 607..698
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 705..799
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 805..900
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFK84949.1"
FT NON_TER 910
FT /evidence="ECO:0000313|EMBL:AFK84949.1"
SQ SEQUENCE 910 AA; 100793 MW; 36ED4AA01891AB6C CRC64;
NSSGTKSAFV TVRVLDTPSP PVNLKVTEVT KDSVSITWEP PLLDGGSKIK NYIVEKREAT
RKSYAAVVTN CHKNSWKIDQ LQEGCSYYFR VTAENEYGIG LPARTADPIK VAEVPQPPGK
ITVDDVTRNS VSLSWTKPEH DGGSKIIQYI VEMQAKQSEK WSECARVKSL EAVITNLTQG
EEYLFRVVAV NEKGRSDPRS LAVPIVAKDL VIEPDVRPAF NSYSVQVGQD LKIEVPISGR
PKPTITWTKD GLPLRQTTRI NVTDSPDQTV LSIKETHKED GGQYGITVAN VVGQKTASIE
IITLDKPDPP KGPVKFDDVS AESITLSWNP PLYTGGCQIT NYIVQKRDTT TTVWDVVSAT
VARTTLKVTK LKTGTEYQFR IFAENRYGQS FALESDPIVA QYPYKEPGPP GTPFVTAISK
DSMVVQWHEP VNNGGSPVIG YHLERKERNS ILWTKVNKTI IHDTQFKAVN LEEGIEYEFR
VYAENIVGVG KASKNSECYV ARDPCDPPGT PEAIIVKRNE ITLQWTKPVY DGGSMITGYI
VEKRDLPEGR WMKASFTNVI ETQFTVSGLT EDQRYEFRVI AKNAAGTVSK PSDSTGPITA
KDEVELPRIS MDPKFRDTIV VNAGETFRLE ADVHGKPLPT IEWLRGDKEI EESARCEIKN
TDFKALLIVK DAIRIDGGQY ILRASNVAGS KSFPVNVKVL DRPGPPEGPV QVTGVTAEKC
TLTWSPPLQD GGSDISHYIV ERRETSRLAW TVVAPEVVTN SLKVTKLLEG NEYIFRIMAV
NKYGVGEPLE SAPVLMKNPF VLPGPPKSLE VTNIAKDSMT VCWNRPDSDG GSEIIGYIVE
KRDRSGIRWI KCNKRRITDL RLRVTGLTED HEYEFRVSAE NAAGVGEPSP ATLYYKACDP
VFKPGPPTNA
//
