ID I3VRU7_THESW Unreviewed; 588 AA.
AC I3VRU7;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Putative signal transduction histidine kinase {ECO:0000313|EMBL:AFK85242.1};
GN OrderedLocusNames=Tsac_0206 {ECO:0000313|EMBL:AFK85242.1};
OS Thermoanaerobacterium saccharolyticum (strain DSM 8691 / JW/SL-YS485).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermoanaerobacterium.
OX NCBI_TaxID=1094508 {ECO:0000313|EMBL:AFK85242.1, ECO:0000313|Proteomes:UP000006178};
RN [1] {ECO:0000313|Proteomes:UP000006178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8691 / JW/SL-YS485 {ECO:0000313|Proteomes:UP000006178};
RA Brown S.D., Land M.L., Herring C.D.;
RT "Thermoanaerobacterium saccharolyticum JW/SL-YS485.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFK85242.1, ECO:0000313|Proteomes:UP000006178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8691 / JW/SL-YS485 {ECO:0000313|Proteomes:UP000006178};
RX PubMed=24907337; DOI=10.1128/AEM.00998-14;
RA Currie D.H., Guss A.M., Herring C.D., Giannone R.J., Johnson C.M.,
RA Lankford P.K., Brown S.D., Hettich R.L., Lynd L.R.;
RT "Profile of Secreted Hydrolases, Associated Proteins, and SlpA in
RT Thermoanaerobacterium saccharolyticum during the Degradation of
RT Hemicellulose.";
RL Appl. Environ. Microbiol. 80:5001-5011(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP003184; AFK85242.1; -; Genomic_DNA.
DR RefSeq; WP_014757165.1; NC_017992.1.
DR AlphaFoldDB; I3VRU7; -.
DR STRING; 1094508.Tsac_0206; -.
DR KEGG; tsh:Tsac_0206; -.
DR PATRIC; fig|1094508.3.peg.206; -.
DR eggNOG; COG2972; Bacteria.
DR BioCyc; TSAC1094508:GLMA-208-MONOMER; -.
DR Proteomes; UP000006178; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000313|EMBL:AFK85242.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:AFK85242.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 464..578
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|SMART:SM00387"
SQ SEQUENCE 588 AA; 68891 MW; 1F39880028E59560 CRC64;
MRELNNKFFY KNLFVLALPL ILIVIVLGSF SILITERYVR DEIYKNSREI LKQSSNDLSI
LFNDINKIYL TFGTNKDVTL YLERILNTNK YSLDDMWHLS MIESLFDSTS FSEPYIQSIY
LYFNNPNKNF LVTGNGINSV TNYIDNKWYD SFLNAPKDEI SWIEVRNLKM YSFDKKGIKV
LSIYKKIANF NGDKIDGVLV LNIYLDYIEN LLNTSTIFPD QKILILDAHD NLICQNINGN
FTGKIDLDNY SKANIITKLE SPNYNIKYVS IVPKKYLYEV PIKLLKMTLV LLLTSIFFVI
LITFRITKRN YENVNKILKI IEAEKTNEIF PEIPVESRDE YSYIIYNIIN SYIEKSQLKM
ELAEKKYKMK AMELLALQSQ ISPHFLSNAL EIIYLRALSY TNGPNDVTKM IENLSQILKY
LLSNPNETVT VKEEIENTKA YIQILKVRYR DKFKVNLIYD ESILSCLMMK LMLQHLIENS
IKHGLKKKNY EGSIKIKIKA VDKKKIKISV IDNGIGMSKE RLNYVKRILD SDFDFYEHIG
LMNTNERLKL LYGKDCEILI RSKLNIGTAV YIIFPYQLKN QNNDDYNK
//
