ID I3VXJ3_THESW Unreviewed; 452 AA.
AC I3VXJ3;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE {ECO:0000256|ARBA:ARBA00013280};
GN OrderedLocusNames=Tsac_2234 {ECO:0000313|EMBL:AFK87238.1};
OS Thermoanaerobacterium saccharolyticum (strain DSM 8691 / JW/SL-YS485).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermoanaerobacterium.
OX NCBI_TaxID=1094508 {ECO:0000313|EMBL:AFK87238.1, ECO:0000313|Proteomes:UP000006178};
RN [1] {ECO:0000313|Proteomes:UP000006178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8691 / JW/SL-YS485 {ECO:0000313|Proteomes:UP000006178};
RA Brown S.D., Land M.L., Herring C.D.;
RT "Thermoanaerobacterium saccharolyticum JW/SL-YS485.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFK87238.1, ECO:0000313|Proteomes:UP000006178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8691 / JW/SL-YS485 {ECO:0000313|Proteomes:UP000006178};
RX PubMed=24907337; DOI=10.1128/AEM.00998-14;
RA Currie D.H., Guss A.M., Herring C.D., Giannone R.J., Johnson C.M.,
RA Lankford P.K., Brown S.D., Hettich R.L., Lynd L.R.;
RT "Profile of Secreted Hydrolases, Associated Proteins, and SlpA in
RT Thermoanaerobacterium saccharolyticum during the Degradation of
RT Hemicellulose.";
RL Appl. Environ. Microbiol. 80:5001-5011(2014).
CC -!- FUNCTION: This protein may play a role in the biosynthesis of the
CC prosthetic group of nitrogenase (FeMo cofactor).
CC {ECO:0000256|ARBA:ARBA00003171}.
CC -!- PATHWAY: Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005155}.
CC -!- SIMILARITY: Belongs to the NifD/NifK/NifE/NifN family.
CC {ECO:0000256|ARBA:ARBA00011002, ECO:0000256|RuleBase:RU004021}.
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DR EMBL; CP003184; AFK87238.1; -; Genomic_DNA.
DR RefSeq; WP_014759075.1; NC_017992.1.
DR AlphaFoldDB; I3VXJ3; -.
DR STRING; 1094508.Tsac_2234; -.
DR KEGG; tsh:Tsac_2234; -.
DR PATRIC; fig|1094508.3.peg.2261; -.
DR eggNOG; COG2710; Bacteria.
DR BioCyc; TSAC1094508:GLMA-2267-MONOMER; -.
DR UniPathway; UPA00782; -.
DR Proteomes; UP000006178; Chromosome.
DR GO; GO:0016163; F:nitrogenase activity; IEA:InterPro.
DR GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR Gene3D; 3.40.50.12380; Nitrogenase MoFe cofactor biosynthesis protein NifE, C-terminal; 1.
DR Gene3D; 3.40.50.1980; Nitrogenase molybdenum iron protein domain; 1.
DR InterPro; IPR000510; Nase/OxRdtase_comp1.
DR InterPro; IPR000318; Nase_comp1_CS.
DR InterPro; IPR005973; NifE.
DR NCBIfam; TIGR01283; nifE; 1.
DR PANTHER; PTHR42956; NITROGENASE IRON-MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN NIFE; 1.
DR PANTHER; PTHR42956:SF1; NITROGENASE IRON-MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN NIFE; 1.
DR Pfam; PF00148; Oxidored_nitro; 1.
DR SUPFAM; SSF53807; Helical backbone' metal receptor; 1.
DR PROSITE; PS00699; NITROGENASE_1_1; 1.
DR PROSITE; PS00090; NITROGENASE_1_2; 1.
PE 3: Inferred from homology;
KW Nitrogen fixation {ECO:0000256|ARBA:ARBA00023231,
KW ECO:0000256|RuleBase:RU004021}.
FT DOMAIN 41..436
FT /note="Nitrogenase/oxidoreductase component 1"
FT /evidence="ECO:0000259|Pfam:PF00148"
SQ SEQUENCE 452 AA; 50470 MW; 7A9CCBA76771E449 CRC64;
MELRLDIPER EKFIKMKGKH HKKEFICNTD SVAGSVSQRA CVYSGARVVL NPIEDAVHLV
HGPIGCASYT WDIRGSLSSG SELFRNSFSS DLKESDVIFG GEEKLSKCID EIYEKYKPKL
IFVYSTCIAG VIGDDIKAVC KESSNKYNIY VVPVESSGFI GNKAAGYKAA CNSLLELIKE
FPVLKKEPLS INYMGDFNLA GEAWIIKGYL NQMGLKVNTI FTGDSNFESL KKATASSLNI
VQCAGSMTYL AKKFEETFGI PYMKVSFLGI EDTSNSLRKI AEFFNDKDVM LKTEKLIEEK
TKMAKHIIEK YKSYLKGKKA AIFVGGGFKA ISLIKQFREL GIDVVVIGTQ NGQKDEYEKI
EEIADYGTVI LDDANPSELE KFMVEKGADI LAGGVKERFL SYKMGISFID HNHDRKHPLS
GYEGAINFAE EVYTTACSPV WKYVKDGVKR YV
//
