ID I4LRC9_GARVA Unreviewed; 324 AA.
AC I4LRC9;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Putative deoxyribonucleoside regulator {ECO:0000313|EMBL:EIK79519.1};
GN ORFNames=CGSMWGv55152_05204 {ECO:0000313|EMBL:EIK79519.1};
OS Gardnerella vaginalis 55152.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Gardnerella.
OX NCBI_TaxID=698955 {ECO:0000313|EMBL:EIK79519.1, ECO:0000313|Proteomes:UP000005936};
RN [1] {ECO:0000313|EMBL:EIK79519.1, ECO:0000313|Proteomes:UP000005936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=55152 {ECO:0000313|EMBL:EIK79519.1,
RC ECO:0000313|Proteomes:UP000005936};
RX PubMed=22609915; DOI=10.1128/JB.00056-12;
RA Ahmed A., Earl J., Retchless A., Hillier S., Rabe L., Cherpes T.,
RA Powell E., Janto B., Eutsey R., Hiller N.L., Boissy R., Dahlgreen M.,
RA Hall B., Costerton J., Post J.C., Hu F., Ehrlich G.;
RT "Comparative Genomic Analyses of 17 Clinical Isolates of Gardnerella
RT vaginalis Provide Evidence of Multiple Genetically Isolated Clades
RT Consistent with Subspeciation into Genovars.";
RL J. Bacteriol. 194:3922-3937(2012).
CC -!- SIMILARITY: Belongs to the SorC transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00010466}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIK79519.1}.
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DR EMBL; ADEQ01000016; EIK79519.1; -; Genomic_DNA.
DR AlphaFoldDB; I4LRC9; -.
DR PATRIC; fig|698955.3.peg.1019; -.
DR Proteomes; UP000005936; Unassembled WGS sequence.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 3.40.50.1360; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000835; HTH_MarR-typ.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR007324; Sugar-bd_dom_put.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR34294:SF11; DEOXYRIBONUCLEOSIDE REGULATOR; 1.
DR PANTHER; PTHR34294; TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR Pfam; PF12802; MarR_2; 1.
DR Pfam; PF04198; Sugar-bind; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}.
FT DOMAIN 7..58
FT /note="HTH marR-type"
FT /evidence="ECO:0000259|Pfam:PF12802"
FT DOMAIN 64..314
FT /note="Sugar-binding"
FT /evidence="ECO:0000259|Pfam:PF04198"
SQ SEQUENCE 324 AA; 36126 MW; AB852121BE3786B8 CRC64;
MKTDQLGMTH KDHQALDVAK LYYNGLSQAE VSEVLHVSRP NVSKLLSHAK KRGFVKITVE
DPREKDIHLI ETLKKYFQLD EVRLVSPIKG RDINLHKSLG KAGSQLIASL LRDGDTIGIS
WSRTIDYVAS QMPEMHFNNI HVVQLRGDMS LPSMDLSMMN ALKAFHLALN ATVHTIAYPI
IFESVEAKQA VERQTGIRNV ISHAEKARIV VYSVGSNEST SPLMSSPLIT NNEKKELTEN
SVGDICSHFV DRNGRVCLPD LNARTLTISL PELRHKEQRI LIAGGNEKLD SIYVALTCKY
ANRLVIDVPT AHKLASICKK SNNS
//
